(Q28506717)

24 January 2017

title

Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345 (English)

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HUS1 checkpoint clamp component

24 January 2017

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GOA release 2020-03-11

Kecheng Jiang

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24 January 2017

Elizabeth Pereira

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24 January 2017

Melissa Maxfield

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24 January 2017

Beatriz Russell

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24 January 2017

Dawn Marie Goudelock

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24 January 2017

Yolanda Sanchez

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24 January 2017

language of work or name

English

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publication date

4 July 2003

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Journal of Biological Chemistry

24 January 2017

published in

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24 January 2017

volume

278

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24 January 2017

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24 January 2017

page(s)

25207–25217

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The DNA damage response: putting checkpoints in perspective

24 January 2017

cites work

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Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast

21 January 2018

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

21 January 2018

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

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Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

21 January 2018

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The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

21 January 2018

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Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage

21 January 2018

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Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9

21 January 2018

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ATR and ATRIP: partners in checkpoint signaling

21 January 2018

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Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

21 January 2018

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ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

21 January 2018

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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

21 January 2018

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

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Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

21 January 2018

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Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway

21 January 2018

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

21 January 2018

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Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

21 January 2018

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Mrc1 transduces signals of DNA replication stress to activate Rad53.

21 January 2018

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CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

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A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

21 January 2018

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The structural basis for 14-3-3:phosphopeptide binding specificity

21 January 2018

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Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

21 January 2018

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Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest

21 January 2018

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Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

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14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

21 January 2018

1 reference

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Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

21 January 2018

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

21 January 2018

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

21 January 2018

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

21 January 2018

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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

21 January 2018

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Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1.

21 January 2018

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Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300070200

Finding nuclear localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300070200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300070200

0 references

1 reference