(Q28383134)

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

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12 November 2019

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity (English)

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12 November 2019

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12 November 2019

Daniel Krappmann

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12 November 2019

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Petra Lemke

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12 November 2019

Ioannis Anagnostopoulos

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12 November 2019

Christine Hacker

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12 November 2019

Stephan Mathas

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12 November 2019

Bernd Dörken

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12 November 2019

Martin Zenke

8

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12 November 2019

Harald Stein

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12 November 2019

Claus Scheidereit

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12 November 2019

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1 September 2002

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12 November 2019

Journal of Experimental Medicine

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12 November 2019

196

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12 November 2019

5

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12 November 2019

605-617

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PMC publication ID

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12 November 2019

Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs

1 reference

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20 March 2017

New insights into the role of nuclear factor-kB in cell growth regulation

1 reference

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20 March 2017

Involvement of chemokine receptors in breast cancer metastasis

1 reference

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20 March 2017

Human T cell lymphotropic virus type I Tax activates IL-15R alpha gene expression through an NF-kappa B site

2 references

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20 March 2017

https://api.crossref.org/works/10.1084/JEM.20020062

22 April 2017

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation

1 reference

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20 March 2017

A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA

1 reference

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20 March 2017

Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells

1 reference

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20 March 2017

Aberrant rel/nfkb genes and activity in human cancer

1 reference

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20 March 2017

Lymphocyte-specific protein 1: a specific marker of human leucocytes

1 reference

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20 March 2017

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

6 April 2017

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

The inducible transcription activator NF-kappa B: regulation by distinct protein subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

20 March 2017

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

7 April 2017

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

7 April 2017

NF-kappa B: ten years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

7 April 2017

Two waves of nuclear factor kappaB recruitment to target promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Novel NEMO/IkappaB kinase and NF-kappa B target genes at the pre-B to immature B cell transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

CD83 is an I-type lectin adhesion receptor that binds monocytes and a subset of activated CD8+ T cells [corrected].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Interaction between host T cells and Reed-Sternberg cells in Hodgkin lymphomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Paradoxical pro-invasive effect of the serine proteinase inhibitor tissue factor pathway inhibitor-2 on human hepatocellular carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

STAT signaling in the pathogenesis and treatment of leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

The molecular and cellular origins of Hodgkin's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Pathological roles of interleukin-15 in adult T-cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Oncogenic alterations of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Expression of a novel Bcl-2 related gene, Bfl-1, in various human cancers and cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Expression of the fructose transporter GLUT5 in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

The nature of Reed-Sternberg cells: phenotype, genotype, and other properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

The nature and action of granulocyte-macrophage colony stimulating factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

29 September 2017

NF-kappaB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1beta, TNF-alpha, and LPS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Classical Hodgkin's disease and follicular lymphoma originating from the same germinal center B cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Tumor necrosis factor receptor-associated factor 1 is overexpressed in Reed-Sternberg cells of Hodgkin's disease and Epstein-Barr virus-transformed lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Rel/NF-kappa B transcription factors and the control of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Regulation and function of adhesion molecules in B-cell chronic lymphocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

The role of adhesion molecules in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

2 June 2018

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20020062

21 January 2018

Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20020062

21 January 2018

High expression of the bcl-x gene in Reed-Sternberg cells of Hodgkin's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194004

27 November 2018

Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology and treatment of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent expression of FAS/APO-1 in Hodgkin's disease and anaplastic large cell lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of B7-2 (CD86) molecules by Reed-Sternberg cells of Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heterogeneous expression of CD80, CD86 and other adhesion molecules on leukemia and lymphoma cells and their induction by interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hodgkin’s cells express CD83, a dendritic cell lineage associated antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CD44 splice variant v10 in Hodgkin's disease is associated with aggressive behaviour and high risk of relapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placental protein 5 in benign and malignant ovarian cyst fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of CD44 gene products for cancer diagnosis and disease evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20020062

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208876%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208876%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208876%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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