(Q28300971)

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Protein tyrosine phosphatases and the immune response

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Europe PubMed Central

Protein tyrosine phosphatases and the immune response (English)

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Tomas Mustelin

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Torkel Vang

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January 2005

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Nature Reviews Immunology

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5

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1

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43-57

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Positive and negative regulation of T-cell activation through kinases and phosphatases

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Protein tyrosine phosphatases in the human genome

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

The protein kinase complement of the human genome

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Subcellular localization of intracellular protein tyrosine phosphatases in T cells

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Crystal structure of the tyrosine phosphatase SHP-2

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Impaired Bone Marrow Microenvironment and Immune Function in T Cell Protein Tyrosine Phosphatase–deficient Mice

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Staging and resetting T cell activation in SMACs

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

PSTPIP: A Tyrosine Phosphorylated Cleavage Furrow–associated Protein that Is a Substrate for a PEST Tyrosine Phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Tyrosine phosphorylation of VHR phosphatase by ZAP-70

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP)

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Identification of a nuclear Stat1 protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Control of vesicle fusion by a tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038/NRI1530

20 April 2017

Role of protein tyrosine phosphatases in T cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

T cell antigen receptor signaling: three families of tyrosine kinases and a phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP).

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Meeting at Mitosis: Cell Cycle-Specific Regulation of c-Src by RPTP

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

CD45: a critical regulator of signaling thresholds in immune cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillations

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Regulation of src family tyrosine kinases in lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Mutational analysis of Lck in CD45-negative T cells: dominant role of tyrosine 394 phosphorylation in kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Immunoreceptor tyrosine-based inhibition motifs

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Hematopoietic cell phosphatase (HCP) regulates p56LCK phosphorylation and ZAP-70 binding to T cell receptor zeta chain

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Inhibitory tyrosine protein kinase p50csk is associated with protein-tyrosine phosphatase PTP-PEST in hemopoietic and non-hemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Extracellular signals and scores of phosphatases: all roads lead to MAP kinase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Enlargement of secretory vesicles by protein tyrosine phosphatase PTP-MEG2 in rat basophilic leukemia mast cells and Jurkat T cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Homotypic secretory vesicle fusion induced by the protein tyrosine phosphatase MEG2 depends on polyphosphoinositides in T cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

New variations of human SHP-1.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

A deletion in the gene encoding the CD45 antigen in a patient with SCID.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Does 77C-->G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Genetic control of serum IgE levels: a study of low molecular weight protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

A point mutation in PTPRC is associated with the development of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

21 January 2018

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Protein tyrosine phosphorylation in T cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Phosphotyrosine phosphatases are involved in reversion of T lymphoblastic proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Membranes from T and B lymphocytes have different patterns of tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Cytoskeletal protein tyrosine phosphatase PTPH1 reduces T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Inhibition of the activity of protein tyrosine phosphate 1C by its SH2 domains.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Intramolecular regulation of protein tyrosine phosphatase SH-PTP1: a new function for Src homology 2 domains

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Lymphocyte activation: the coming of the protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Regulation of the low molecular weight phosphotyrosine phosphatase by phosphorylation at tyrosines 131 and 132.

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Lck Dephosphorylation at Tyr-394 and Inhibition of T Cell Antigen Receptor Signaling by Yersinia Phosphatase YopH

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

31 March 2020

Phenylarsine oxide augments tyrosine phosphorylation in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRI1530

7 January 2021

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10.1038/NRI1530

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1 reference

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