(Q28284176)

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Tetraspanin functions and associated microdomains

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Tetraspanin functions and associated microdomains (English)

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Martin E Hemler

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October 2005

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Nature Reviews Molecular Cell Biology

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6

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10

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801-11

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CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs.

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

A novel 2 bp deletion in the TM4SF2 gene is associated with MRX58

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Characterization of mice lacking the tetraspanin superfamily member CD151

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

The gamete fusion process is defective in eggs of Cd9-deficient mice

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Severely reduced female fertility in CD9-deficient mice

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Tetraspanin protein CD9 is a novel paranodal component regulating paranodal junctional formation

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Function of the tetraspanin CD151-alpha6beta1 integrin complex during cellular morphogenesis

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

PDZ domains: structural modules for protein complex assembly

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Tetraspanin CD81 is linked to ERK/MAPKinase signaling by Shc in liver tumor cells

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathway

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

The palmitoylation of metastasis suppressor KAI1/CD82 is important for its motility- and invasiveness-inhibitory activity

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Palmitoylation of intracellular signaling proteins: regulation and function

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Specific tetraspanin functions

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

1 reference

https://api.crossref.org/works/10.1038/NRM1736

21 April 2017

Functions of lipid rafts in biological membranes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

21 April 2017

Tetraspanins: molecular organisers of the leukocyte surface

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane Microdomain

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin superfamily in insects

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Structure of the Tetraspanin Main Extracellular Domain

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The role of the peripherin/RDS gene in retinal dystrophies

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

An extracellular site on tetraspanin CD151 determines alpha 3 and alpha 6 integrin-dependent cellular morphology

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin superfamily member CD151 regulates outside-in integrin alphaIIbbeta3 signaling and platelet function.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A regulatory role for CD37 in T cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Normal lymphocyte development but delayed humoral immune response in CD81-null mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin microdomains in immune cell signalling and malignant disease.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin web modulates immune-signalling complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Requirement of CD9 on the egg plasma membrane for fertilization

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Allergen-induced airway hyperreactivity is diminished in CD81-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Cell surface monkey CD9 antigen is a coreceptor that increases diphtheria toxin sensitivity and diphtheria toxin receptor affinity

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin protein (TSP-15) is required for epidermal integrity in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

PLS1, a gene encoding a tetraspanin-like protein, is required for penetration of rice leaf by the fungal pathogen Magnaporthe grisea

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin BcPls1 is required for appressorium-mediated penetration of Botrytis cinerea into host plant leaves.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A new class of tetraspanins in fungi.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Integrin associated proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The CD81 tetraspanin facilitates instantaneous leukocyte VLA-4 adhesion strengthening to vascular cell adhesion molecule 1 (VCAM-1) under shear flow.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Protein kinase C and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

EWI-2 modulates lymphocyte integrin alpha4beta1 functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Possible role of coexpression of CD9 with membrane-anchored heparin-binding EGF-like growth factor and amphiregulin in cultured human keratinocyte growth

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

CD151 regulates epithelial cell–cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin CD151 functions as a negative regulator in the adhesion-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Requirement of the p130CAS-Crk Coupling for Metastasis Suppressor KAI1/CD82-mediated Inhibition of Cell Migration

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Structure of the major membrane protein complex from urinary bladder epithelial cells by cryo-electron crystallography

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Expression of the palmitoylation-deficient CD151 weakens the association of alpha 3 beta 1 integrin with the tetraspanin-enriched microdomains and affects integrin-dependent signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

CD81 associates with 14-3-3 in a redox-regulated palmitoylation-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Palmitoylation supports assembly and function of integrin-tetraspanin complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Compartmentalization of integrin α6β4 signaling in lipid rafts

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

A physical and functional link between cholesterol and tetraspanins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside).

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin CD81 is necessary for partitioning of coligated CD19/CD21-B cell antigen receptor complexes into signaling-active lipid rafts

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

B cell signaling is regulated by induced palmitoylation of CD81.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Functional domains in tetraspanin proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Increased brain size and glial cell number in CD81-null mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

31 March 2020

Tetraspanins and malignancy

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

7 January 2021

based on heuristic

inferred from DOI database lookup

Tetraspanin CD82 attenuates cellular morphogenesis through down-regulating integrin alpha6-mediated cell adhesion

1 reference

https://api.crossref.org/works/10.1038%2FNRM1736

7 January 2021

based on heuristic

inferred from DOI database lookup

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