(Q28275730)

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Enhancement of antitumor immunity by CTLA-4 blockade

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Enhancement of antitumor immunity by CTLA-4 blockade (English)

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D R Leach

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M F Krummel

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J P Allison

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language of work or name

English

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publication date

22 March 1996

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published in

Science

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volume

271

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issue

5256

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page(s)

1734-6

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cites work

CTLA-4 can function as a negative regulator of T cell activation

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/1074-7613(94)90071-X

CD28-B7 interactions in T-cell activation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

The role of the CD28 receptor during T cell responses to antigen

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

CTLA4 mediates antigen-specific apoptosis of human T cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Dendritic cells as initiators of tumor immune responses: a possible strategy for tumor immunotherapy?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

The Yin and Yang of T cell costimulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Manipulation of costimulatory signals to enhance antitumor T-cell responses.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

The B7 and CD28 receptor families

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

New perspectives of CD28-B7-mediated T cell costimulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

The ups and downs of T cell costimulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

A new member of the immunoglobulin superfamily--CTLA-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.271.5256.1734

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