(Q28249019)

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Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

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Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency (English)

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Xiaomeng Long

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Sara Ortiz-Vega

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Yenshou Lin

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Joseph Avruch

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language of work or name

English

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publication date

24 June 2005

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published in

Journal of Biological Chemistry

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volume

280

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issue

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page(s)

23433-6

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cites work

Tor signalling in bugs, brain and brawn

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Upstream and downstream of mTOR

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reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Rheb binds and regulates the mTOR kinase

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reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

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Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Rheb promotes cell growth as a component of the insulin/TOR signalling network

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stated in

Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

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stated in

Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

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reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

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stated in

Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1074%2FJBC.C500169200

retrieved

21 January 2018

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