(Q28214998)

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Neuronal nicotinic receptors: from protein structure to function

scientific article (publication date: 31 August 2001)

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Neuronal nicotinic receptors: from protein structure to function (English)

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protein structure

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V Itier

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D Bertrand

2

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31 August 2001

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504

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3

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118-25

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Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

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21 January 2018

A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Genomic Sequences Encoding the -Subunit of Acetylcholine Receptor Are Conserved in Evolution

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Functional expression of a new pharmacological subtype of brain nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (alpha 5) in the rat central nervous system

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Presynaptic ionotropic receptors

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Neuronal Nicotinic Receptor Subtypes

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Neuronal nicotinic acetylcholine receptors: from the gene to the disease

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Long-term potentiation of excitatory inputs to brain reward areas by nicotine

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Overview of nicotinic receptors and their roles in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotine facilitates noradrenaline release in the rat supraoptic nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotine activates and desensitizes midbrain dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotinic acetylcholine receptors in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Chemical kinetic measurements of transmembrane processes using rapid reaction techniques: acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Acetylcholine receptor: channel-opening kinetics evaluated by rapid chemical kinetic and single-channel current measurements

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Subunit interface selective toxins as probes of nicotinic acetylcholine receptor structure

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Molecular modelling of the nicotinic acetylcholine receptor transmembrane region in the open state

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

A model of the nicotinic receptor extracellular domain based on sequence identity and residue location

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Pharmacology and biophysical properties of alpha 7 and alpha 7-alpha 8 alpha-bungarotoxin receptor subtypes immunopurified from the chick optic lobe

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Nicotinic receptors at the amino acid level

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

End-plate channel opening and the kinetics of quinacrine (mepacrine) block

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

The permeability of the endplate channel to organic cations in frog muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Stratification of the channel domain in neurotransmitter receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Electrostatics and the ion selectivity of ligand-gated channels

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Kinked-helices model of the nicotinic acetylcholine receptor ion channel and its complexes with blockers: simulation by the Monte Carlo minimization method

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Agonist-induced closure of constitutively open gamma-aminobutyric acid channels with mutated M2 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Role of two acetylcholine receptor subunit domains in homomer formation and intersubunit recognition, as revealed by alpha 3 and alpha 7 subunit chimeras

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Progesterone modulates a neuronal nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Acetylcholine receptor channel imaged in the open state

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

21 January 2018

Phosphorylation of the predicted major intracellular domains of the rat and chick neuronal nicotinic acetylcholine receptor alpha 7 subunit by cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Chick optic lobe contains a developmentally regulated alpha2alpha5beta2 nicotinic receptor subtype.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Functional alpha6-containing nicotinic receptors are present in chick retina

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

An alpha4beta4 nicotinic receptor subtype is present in chick retina: identification, characterization and pharmacological comparison with the transfected alpha4beta4 and alpha6beta4 subtypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Alpha7 and alpha8 nicotinic receptor subtypes immunopurified from chick retina have different immunological, pharmacological and functional properties

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Electrophysiology of a chick neuronal nicotinic acetylcholine receptor expressed in Xenopus oocytes after cDNA injection

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement1Published on the World Wide Web on 24 October 1997.1

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Quantitative measurement of calcium flux through muscle and neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

A molecular link between inward rectification and calcium permeability of neuronal nicotinic acetylcholine alpha3beta4 and alpha4beta2 receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Single channel currents in the nicotinic acetylcholine receptor: a direct demonstration of allosteric transitions

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

Subunit-dependent modulation of neuronal nicotinic receptors by zinc.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902702-8

7 January 2021

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