(Q28202486)

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David Frendewey

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Nicholas W Gale

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Wojtek Auerbach

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William T Poueymirou

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Niels C Adams

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Jose Rojas

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Jason Yasenchak

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Rostislav Chernomorsky

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Marylene Boucher

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Andrea L Elsasser

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Lakeisha Esau

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Jenny Zheng

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Jennifer A Griffiths

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Xiaorong Wang

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Hong Su

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Yingzi Xue

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Melissa G Dominguez

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Irene Noguera

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Richard Torres

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Lynn E Macdonald

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A Francis Stewart

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Thomas M DeChiara

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George D Yancopoulos

Initial sequencing and analysis of the human genome

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language of work or name

English

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publication date

June 2003

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652-9

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cites work

1 reference

7 January 2021

The Sequence of the Human Genome

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7 January 2021

Laskers for 2001: knockout mice and test-tube babies

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7 January 2021

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7 January 2021

Generating mice with targeted mutations

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7 January 2021

Forty years with homologous recombination

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7 January 2021

Contemporary gene targeting strategies for the novice

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7 January 2021

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

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7 January 2021

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

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7 January 2021

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

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7 January 2021

Functional analysis of secreted and transmembrane proteins critical to mouse development.

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7 January 2021

Defining brain wiring patterns and mechanisms through gene trapping in mice.

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7 January 2021

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome

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7 January 2021

BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin

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7 January 2021

A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA

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7 January 2021

BAC to the future: the use of bac transgenic mice for neuroscience research

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7 January 2021

The length of homology required for gene targeting in embryonic stem cells

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7 January 2021

Reexamination of Gene Targeting Frequency as a Function of the Extent of Homology between the Targeting Vector and the Target Locus

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7 January 2021

Targeting frequency for deletion vectors in embryonic stem cells

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7 January 2021

Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology

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7 January 2021

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

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7 January 2021

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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7 January 2021

Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination

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7 January 2021

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

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7 January 2021

Multiple developmental roles of VEGF suggested by a LacZ-tagged allele.

1 reference

7 January 2021

A new logic for DNA engineering using recombination in Escherichia coli

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7 January 2021

Rapid modification of bacterial artificial chromosomes by ET-recombination.

1 reference

7 January 2021

Efficient and precise engineering of a 200 kb beta-globin human/bacterial artificial chromosome in E. coli DH10B using an inducible homologous recombination system

1 reference

7 January 2021

Simplified generation of targeting constructs using ET recombination

1 reference

7 January 2021

An efficient recombination system for chromosome engineering in Escherichia coli

1 reference

7 January 2021

Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA.

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7 January 2021

A physical map of the mouse genome

1 reference

7 January 2021

Identification of ubiquitin ligases required for skeletal muscle atrophy

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7 January 2021

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

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7 January 2021

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

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7 January 2021

Establishment and chimera analysis of 129/SvEv- and C57BL/6-derived mouse embryonic stem cell lines.

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7 January 2021

Use of coisogenic host blastocysts for efficient establishment of germline chimeras with C57BL/6J ES cell lines

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7 January 2021

A test of a climate room for preparation of chromosome slides

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7 January 2021

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization

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7 January 2021

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

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7 January 2021

Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene.

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7 January 2021

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

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7 January 2021