(Q28143066)

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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

scientific article (publication date: August 2000)

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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages (English)

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DOI.org query endpoint

https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

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Peter J. Ratcliffe

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Peter J. Ratcliffe

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22 April 2017

7

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Adrian L. Harris

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

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Katherine L. Talks

1

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Helen Turley

2

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Kevin C. Gatter

3

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Patrick H. Maxwell

4

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Christopher W. Pugh

5

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

language of work or name

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publication date

August 2000

1 reference

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

The American Journal of Pathology

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

157

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

2

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https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

411-421

1 reference

DOI.org query endpoint

https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

2 references

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20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

7 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Regulation of vascular endothelial growth factor expression by insulin-like growth factor I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Oxygen regulated gene expression: erythropoietin as a model system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Oxygen sensing and molecular adaptation to hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

29 September 2017

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

2 June 2018

Oxygen(es) and the hypoxia-inducible factor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

2 June 2018

A reaction-diffusion model of cancer invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

2 June 2018

PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

2 June 2018

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

27 November 2018

Tumor hypoxia in pelvic recurrences of cervical cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

27 November 2018

Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850121

27 November 2018

Influence of the hypoxic subvolume on the survival of patients with head and neck cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

Targeting gene expression to hypoxic tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

EPAS1 trans-activation during hypoxia requires p42/p44 MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

Tumor induction of VEGF promoter activity in stromal cells

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964554-3

7 January 2021

PR39, a peptide regulator of angiogenesis

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7 January 2021

Diagnostic application of monoclonal antibody KB90 (CD11c) in acute myeloid leukaemia

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7 January 2021

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/10934146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of hypoxia in the maintenance of hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10934146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)64554-3

2 references

DOI.org query endpoint

https://doi.org/10.1016%2FS0002-9440%2810%2964554-3

22 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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