(Q28140732)

GOA release 2020-03-11

author name string

A Guo

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P Salomoni

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J Luo

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A Shih

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S Zhong

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W Gu

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P P Pandolfi

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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language of work or name

English

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publication date

October 2000

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730-6

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cites work

1 reference

7 January 2021

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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7 January 2021

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

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7 January 2021

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

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7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

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7 January 2021

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML

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7 January 2021

The transcriptional role of PML and the nuclear body

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7 January 2021

Role of PML in cell growth and the retinoic acid pathway

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7 January 2021

PML is essential for multiple apoptotic pathways

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7 January 2021

Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

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7 January 2021

A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins

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7 January 2021

Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling

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7 January 2021

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

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7 January 2021

Composite co-activator ARC mediates chromatin-directed transcriptional activation

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7 January 2021

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

BCL-2 family: regulators of cell death

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7 January 2021

Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.

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7 January 2021

Rearrangement of the p53 gene in human osteogenic sarcomas

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

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7 January 2021

Synergistic activation of transcription by CBP and p53

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7 January 2021

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

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7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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7 January 2021

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

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7 January 2021

Identification and classification of p53-regulated genes

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7 January 2021

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

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7 January 2021

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

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7 January 2021

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

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7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

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7 January 2021

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

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7 January 2021

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

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7 January 2021

Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

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7 January 2021

A role for PML and the nuclear body in genomic stability

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7 January 2021

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

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7 January 2021

Frequency of RAS and p53 mutations in acute promyelocytic leukemias

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7 January 2021

Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

1 reference

7 January 2021