(Q28115037)

3 January 2017

title

A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation (English)

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LYN proto-oncogene, Src family tyrosine kinase

3 January 2017

main subject

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protein tyrosine kinase activity

GOA release 2020-03-11

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GOA release 2020-03-11

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David Holowka

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3 January 2017

Barbara Baird

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3 January 2017

Ryan M. Young

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3 January 2017

language of work or name

English

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publication date

6 June 2003

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Journal of Biological Chemistry

3 January 2017

published in

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3 January 2017

volume

278

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3 January 2017

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3 January 2017

page(s)

20746–20752

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The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology

3 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

The unique domain as the site on Lyn kinase for its constitutive association with the high affinity receptor for IgE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Interaction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Fc(epsilon)RI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Quantitative Analysis of Phospholipids in Functionally Important Membrane Domains from RBL-2H3 Mast Cells Using Tandem High-Resolution Mass Spectrometry†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Structure and origin of ordered lipid domains in biological membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Membrane compartmentation is required for efficient T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Fluorescence anisotropy measurements of lipid order in plasma membranes and lipid rafts from RBL-2H3 mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Plasma membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Microdomain-dependent regulation of Lck and Fyn protein-tyrosine kinases in T lymphocyte plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Spontaneous phosphorylation of the receptor with high affinity for IgE in transfected fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Lyn, a src-like tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Autophosphorylation induces autoactivation and a decrease in the Src homology 2 domain accessibility of the Lyn protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Roles of C-terminal Src kinase in the initiation and the termination of the high affinity IgE receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Functional analysis of Csk in signal transduction through the B-cell antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Cholesterol depletion induces large scale domain segregation in living cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Cutting Edge: Transmembrane phosphoprotein Csk-binding protein/phosphoprotein associated with glycosphingolipid-enriched microdomains as a negative feedback regulator of mast cell signaling through the FcepsilonRI

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Detergent-resistant microdomains offer no refuge for proteins phosphorylated by the IgE receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

Partitioning of lipidated peptide sequences into liquid-ordered lipid domains in model and biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211402200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211402200

0 references

1 reference