(Q27930631)

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The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum

scientific article published on June 15, 1993

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scholarly article

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PubMed publication ID

1 December 2016

The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum (English)

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PubMed publication ID

1 December 2016

endoplasmic reticulum

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Saccharomyces cerevisiae

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immunosuppression

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based on heuristic

inferred from title

tacrolimus binding proteins

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

fungal gene expression regulation

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

author name string

J. A. Partaledis

1

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

V. Berlin

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

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publication date

15 June 1993

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full work available at URL

http://www.pnas.org/content/90/12/5450.full.pdf

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

https://europepmc.org/articles/PMC46738

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

https://europepmc.org/articles/PMC46738?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685904

17 August 2024

https://pnas.org/doi/pdf/10.1073/pnas.90.12.5450

1 reference

10.1073/PNAS.90.12.5450

https://api.crossref.org/works/10.1073/PNAS.90.12.5450

17 August 2024

Proceedings of the National Academy of Sciences of the United States of America

1 reference

PubMed publication ID

1 December 2016

90

0 references

12

0 references

5450-4

0 references

Order of events in the yeast secretory pathway

1 reference

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20 March 2017

Control of yeast cell type by the mating type locus: Positive regulation of the α-specific STE3 gene by the MATα 1 product

1 reference

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1 reference

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20 March 2017

Characterization of a gene product (Sec53p) required for protein assembly in the yeast endoplasmic reticulum

1 reference

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The yeast SEC53 gene encodes phosphomannomutase.

1 reference

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KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene

1 reference

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Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors

1 reference

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20 March 2017

The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins

1 reference

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20 March 2017

Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

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s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin

1 reference

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20 March 2017

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1 reference

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20 March 2017

FK506 binding protein associated with the calcium release channel (ryanodine receptor)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

10 Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast

1 reference

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20 March 2017

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

20 March 2017

Protein folding in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

7 April 2017

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

7 April 2017

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

7 April 2017

Cyclophilins: a new family of proteins involved in intracellular folding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

29 September 2017

Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene

1 reference

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29 September 2017

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum

1 reference

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29 September 2017

Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains

1 reference

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29 September 2017

Structure and regulation of a nuclear gene in Saccharomyces cerevisiae that specifies MRP13, a protein of the small subunit of the mitochondrial ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46738

29 September 2017

A highly conserved sequence in yeast heat shock gene promoters

1 reference

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29 September 2017

Transcriptional regulation of an hsp70 heat shock gene in the yeast Saccharomyces cerevisiae

1 reference

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Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site

1 reference

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SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum

1 reference

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Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins

1 reference

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The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins

1 reference

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A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins

1 reference

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PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism

1 reference

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Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae

1 reference

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Catalysis of protein folding by prolyl isomerase

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S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP.

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Saccharomyces cerevisiae contains a homolog of human fkbp‐13, a membrane‐associated fk506/rapamycin binding protein

1 reference

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The cyclophilin homolog ninaA is required in the secretory pathway

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The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685904

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Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast

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Invariant chain--a regulator of antigen presentation

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Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heat shock proteins

1 reference

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Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1 reference

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Isomerase and chaperone activity of prolyl isomerase in the folding of carbonic anhydrase

1 reference

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Thermal stability and folding of type IV procollagen and effect of peptidyl-prolyl cis-trans-isomerase on the folding of the triple helix

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Identifiers

10.1073/PNAS.90.12.5450

0 references

1993PNAS...90.5450P

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PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

1 December 2016

ResearchGate publication ID

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