(Q27765381)

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B J Canagarajah

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J C Boehm

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S Kassisà

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M H Cobb

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P R Young

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S Abdel-Meguid

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J L Adams

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E J Goldsmith

MAP kinases ERK1 and ERK2: pleiotropic enzymes in a ubiquitous signaling network

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publication date

15 September 1998

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1117-28

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cites work

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The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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Parallel signal processing among mammalian MAPKs

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Hyperexpression of mitogen-activated protein kinase in human breast cancer

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An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

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The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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Sounding the alarm: protein kinase cascades activated by stress and inflammation

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

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Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

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A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

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The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

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Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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Crystal structure of p38 mitogen-activated protein kinase

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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The effect of quercetin on the phosphorylatio activity of the Rous sarcoma virus transforming gene product in vitro and in vivo

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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7 January 2021

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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7 January 2021

Crystal structure of cyclin-dependent kinase 2

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Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

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Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

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Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

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Hydrogen bonding in globular proteins

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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

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Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors

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SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

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7 January 2021

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

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7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

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7 January 2021

The glycine-rich sequence of protein kinases: a multifunctional element

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7 January 2021

Active and inactive protein kinases: structural basis for regulation

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7 January 2021

Improved Fourier coefficients for maps using phases from partial structures with errors

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7 January 2021

The CCP4 suite: programs for protein crystallography

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7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

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7 January 2021

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

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10.1016/S0969-2126(98)00113-0

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

9753691

1 reference

Consolidated OpenCitations Corpus – April 2017