(Q27681196)

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Zhonghua Wang

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Bon-Kyung Koo

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Anooj Patel

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Kathleen Collins

It all comes together at the ends: telomerase structure, function, and biogenesis

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publication date

13 July 2012

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16-26

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cites work

1 reference

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Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

20 March 2017

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20 March 2017

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Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element

20 March 2017

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Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin

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The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

20 March 2017

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Alpha helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex

20 March 2017

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Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

20 March 2017

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Dali server: conservation mapping in 3D

20 March 2017

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20 March 2017

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Molecular replacement with MOLREP

20 March 2017

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Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Automated NMR structure calculation with CYANA

20 March 2017

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20 March 2017

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A graphical user interface to the CCP4 program suite

20 March 2017

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Refinement of protein structures in explicit solvent

20 March 2017

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

20 March 2017

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20 March 2017

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7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor

20 March 2017

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20 March 2017

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Structure and function of telomerase RNA

20 March 2017

1 reference

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Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

20 March 2017

1 reference

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Specificity of ribonucleoprotein interaction determined by RNA folding during complex formulation

20 March 2017

1 reference

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

20 March 2017

1 reference

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Conserved and divergent features of the structure and function of La and La-related proteins (LARPs)

20 March 2017

1 reference

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Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

20 March 2017

1 reference

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Advances in the understanding of dyskeratosis congenita

20 March 2017

1 reference

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RNA recognition motifs: boring? Not quite

7 April 2017

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Reverse transcriptase motifs in the catalytic subunit of telomerase

7 April 2017

1 reference

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The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids

7 April 2017

1 reference

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The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA.

7 April 2017

1 reference

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Role of telomeres and telomerase in cancer

29 September 2017

1 reference

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Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein

29 September 2017

1 reference

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An intrinsically disordered C terminus allows the La protein to assist the biogenesis of diverse noncoding RNA precursors

29 September 2017

1 reference

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Telomerase structure function.

29 September 2017

1 reference

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Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants

29 September 2017

1 reference

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Telomerase: an RNP enzyme synthesizes DNA.

29 September 2017

1 reference

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Multiple mechanisms for elongation processivity within the reconstituted tetrahymena telomerase holoenzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Telomeres and telomerase in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Precursor-product discrimination by La protein during tRNA metabolism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

The structure and function of telomerase reverse transcriptase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

The maintenance and masking of chromosome termini

29 September 2017

1 reference

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A novel RNA binding domain in tetrahymena telomerase p65 initiates hierarchical assembly of telomerase holoenzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Holoenzyme proteins required for the physiological assembly and activity of telomerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Telomerase RNA structure and function: implications for dyskeratosis congenita.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Telomere maintenance and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

The Euplotes La motif protein p43 has properties of a telomerase-specific subunit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Ciliate telomerase RNA loop IV nucleotides promote hierarchical RNP assembly and holoenzyme stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

A comprehensive analysis of the La-motif protein superfamily

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Structure of stem-loop IV of Tetrahymena telomerase RNA.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Biological and biochemical functions of RNA in the tetrahymena telomerase holoenzyme

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398246

Solution structure of YKR049C, a putative redox protein from Saccharomyces cerevisiae

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22705372