(Q27640149)

object named as

Juan Carlos Izpisua Belmonte

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Aris N Economides

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Markus Affolter

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Senyon Choe

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Witek Kwiatkowski

object named as

Witek Kwiatkowski

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author name string

Jay Groppe

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Jason Greenwald

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Ezra Wiater

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Joaquin Rodriguez-Leon

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Wylie W Vale

TGF-beta signal transduction

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language of work or name

English

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publication date

12 December 2002

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published in

Nature

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volume

420

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issue

6916

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page(s)

636-42

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cites work

1 reference

TGF beta inhibitors. New and unexpected requirements in vertebrate development

21 April 2017

1 reference

Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton

21 April 2017

1 reference

Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis

21 April 2017

1 reference

Mutations of the NOG gene in individuals with proximal symphalangism and multiple synostosis syndrome

21 April 2017

1 reference

Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients

21 April 2017

1 reference

Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily

21 April 2017

1 reference

BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II

21 April 2017

1 reference

Crystal structure of the BMP-2-BRIA ectodomain complex

21 April 2017

1 reference

Identification of the ligand-binding site of the BMP type IA receptor for BMP-4

21 April 2017

1 reference

BMP/GDF-signalling interactions during synovial joint development

21 April 2017

1 reference

Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes

21 April 2017

1 reference

Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding

21 April 2017

1 reference

Automated MAD and MIR structure solution

21 April 2017

1 reference

The CCP4 suite: programs for protein crystallography

21 April 2017

1 reference

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Bone: formation by autoinduction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Identical mutations in NOG can cause either tarsal/carpal coalition syndrome or proximal symphalangism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Noggin antagonizes BMP signaling to create a niche for adult neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Induction of a noggin-like gene by ectopic DV interaction during planarian regeneration

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Novel approach to phasing proteins: derivatization by short cryo-soaking with halides

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Evolution and Classification of Cystine Knot-Containing Hormones and Related Extracellular Signaling Molecules

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

DAN is a secreted glycoprotein related to Xenopus cerberus.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

https://api.crossref.org/works/10.1038%2FNATURE01245

1 reference

7 January 2021

The Cystine-Knot Growth-Factor Superfamily

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Endogenous and ectopic expression of noggin suggests a conserved mechanism for regulation of BMP function during limb and somite patterning

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Morphogenesis of digits in the avian limb is controlled by FGFs, TGFbetas, and noggin through BMP signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Requirement for BMP signaling in interdigital apoptosis and scale formation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Identification of a novel NOG gene mutation (P35S) in an Italian family with symphalangism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Identification of mammalian noggin and its expression in the adult nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021

Multiple protein sequence alignment from tertiary structure comparison: assignment of global and residue confidence levels

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01245

7 January 2021