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Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition

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Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition (English)

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M Simonovic

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Gettins PGW

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K Volz

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August 2000

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1423-7

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Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

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Prevention of vertebrate neuronal death by the crmA gene

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Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

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Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution

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Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

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Structural basis for serpin inhibitor activity

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Stereochemically restrained refinement of macromolecular structures

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PubMed publication ID

10975564

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ResearchGate publication ID

12345814

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