(Q27620372)

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M E Noble

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J A Endicott

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L N Johnson

Cyclin-dependent kinases: engines, clocks, and microprocessors

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language of work or name

English

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publication date

November 1999

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438-43

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cites work

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7 January 2021

Crystal structure of cyclin-dependent kinase 2

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7 January 2021

The crystal structure of cyclin A

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7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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7 January 2021

Structural basis of cyclin-dependent kinase activation by phosphorylation

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7 January 2021

Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

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7 January 2021

Use of an oriented peptide library to determine the optimal substrates of protein kinases

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7 January 2021

Differences in substrate specificity between Cdk2-cyclin A and Cdk2-cyclin E in vitro

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7 January 2021

A predictive scale for evaluating cyclin-dependent kinase substrates. A comparison of p34cdc2 and p33cdk2.

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7 January 2021

Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs

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7 January 2021

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

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7 January 2021

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

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7 January 2021

Cyclin-binding motifs are essential for the function of p21CIP1

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7 January 2021

Specific regulation of E2F family members by cyclin-dependent kinases

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7 January 2021

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

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7 January 2021

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

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7 January 2021

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

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7 January 2021

Targets of cyclin-dependent protein kinases.

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7 January 2021

Differential phosphorylation of T-47D human breast cancer cell substrates by D1-, D3-, E-, and A-type cyclin-CDK complexes

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7 January 2021

Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein

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7 January 2021

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

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7 January 2021

The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition

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7 January 2021

Catalytic mechanism of phosphorylase kinase probed by mutational studies

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7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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7 January 2021

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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7 January 2021

Identification of substrate binding site of cyclin-dependent kinase 5

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7 January 2021

Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits

1 reference

7 January 2021

AMoRe: an automated package for molecular replacement

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7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

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7 January 2021

Improved Fourier coefficients for maps using phases from partial structures with errors

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Automated refinement of protein models

1 reference

7 January 2021