(Q27551249)

English

Srb5p YGR104C

fungal protein found in Saccharomyces cerevisiae S288c

Srb5p
YGR104C
SRB5

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Statements

1 reference

25 May 2022

1 reference

10 December 2016

Mediator complex, subunit Med18

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P32585

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

transcription coregulator activity

4 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IBA

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

9 May 2019

Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

6 references

9 May 2019

The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

Identification, structure, and functional requirement of the Mediator submodule Med7N/31

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

9 May 2019

A high resolution protein interaction map of the yeast Mediator complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IPI

transcription coregulator activity

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

determination method

IEA

cell component

core mediator complex

1 reference

21 June 2018

Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation

GOA

curator

SGD

Saccharomyces Genome Database ID

S000003336

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IEA

biological process

regulation of transcription by RNA polymerase II

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IEA

transcription open complex formation at RNA polymerase II promoter

1 reference

9 May 2019

Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IMP

RNA polymerase II preinitiation complex assembly

1 reference

9 May 2019

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IDA

transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

determination method

IEA

termination of RNA polymerase II transcription

1 reference

21 June 2018

Srb5/Med18-mediated termination of transcription is dependent on gene looping

GOA

curator

SGD

Saccharomyces Genome Database ID

S000003336

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

determination method

IMP

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585

determination method

IDA

regulation of transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585

determination method

IEA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

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