(Q27549263)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06697

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II complex binding

RNA polymerase II C-terminal domain phosphoserine binding

1 reference

9 May 2019

Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

chromatin binding

1 reference

9 May 2019

Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

protein binding

6 references

9 May 2019

Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

RNA polymerase II complex binding

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

cell component

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

1 reference

9 May 2019

Cdc73/Paf1 complex

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

5 June 2018

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

5 June 2018

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

5 June 2018

Cdc73/Paf1 complex

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

biological process

histone modification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

1 reference

9 May 2019

positive regulation of transcription elongation from RNA polymerase II promoter

1 reference

5 June 2018

Molecular evidence indicating that the yeast PAF complex is required for transcription elongation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex

1 reference

5 June 2018

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

1 reference

5 June 2018

positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues

1 reference

9 May 2019

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

transcription elongation from RNA polymerase I promoter

1 reference

9 May 2019

The Paf1 complex is required for efficient transcription elongation by RNA polymerase I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

positive regulation of transcription elongation from RNA polymerase I promoter

1 reference

9 May 2019

The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

regulation of transcription-coupled nucleotide-excision repair

IGI

1 reference

9 May 2019

Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

IGI

mRNA 3'-end processing

1 reference

9 May 2019

The Paf1 complex has functions independent of actively transcribing RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

regulation of histone H2B conserved C-terminal lysine ubiquitination

1 reference

9 May 2019

Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

positive regulation of histone H3-K36 trimethylation

1 reference

9 May 2019

Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

negative regulation of DNA recombination

1 reference

9 May 2019

A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06697

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06697&geneProductId=UniProtKB:Q06697

1 reference

5 June 2018

positive regulation of transcription elongation from RNA polymerase II promoter

recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference