(Q27547632)

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53335&geneProductId=UniProtKB:P53335

10 September 2018

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53335&geneProductId=UniProtKB:P53335

10 September 2018

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53335&geneProductId=UniProtKB:P53335

enzyme activator activity

IGI

1 reference

14 February 2019

The telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p during ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

1 reference

14 February 2019

protein binding

3 references

14 February 2019

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

14 February 2019

The splicing ATPase prp43p is a component of multiple preribosomal particles

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

telomerase inhibitor activity

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

14 February 2019

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

IGI

cell component

nucleoplasm

IDA

1 reference

14 February 2019

The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

IDA

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

1 reference

14 February 2019

box C/D RNA 3'-end processing

biological process

1 reference

14 February 2019

The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

1 reference

14 February 2019

ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

1 reference

14 February 2019

negative regulation of telomere maintenance via telomerase

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

14 February 2019

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

14 February 2019

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

positive regulation of catalytic activity

IGI

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

negative regulation of telomerase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53335

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P53335

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference