(Q27024060)

title

Modeling inherited cardiac disorders (English)

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author name string

Karim Sallam

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

Kazuki Kodo

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

Joseph C Wu

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

language of work or name

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2014

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

page(s)

784-794

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

14 May 2020

cites work

1 reference

12 December 2020

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

1 reference

12 December 2020

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

1 reference

12 December 2020

Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing

1 reference

12 December 2020

Functional significance of KCNH2 (HERG) K897T polymorphism for cardiac repolarization assessed by analysis of T-wave morphology.

1 reference

12 December 2020

Lamin A/C and cardiac diseases

1 reference

12 December 2020

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

12 December 2020

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

12 December 2020

A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response

1 reference

12 December 2020

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

1 reference

12 December 2020

Repolarization reserve: a moving target

1 reference

12 December 2020

Protective effect of KCNH2 single nucleotide polymorphism K897T in LQTS families and identification of novel KCNQ1 and KCNH2 mutations

1 reference

12 December 2020

SCN5A overlap syndromes: no end to disease complexity?

1 reference

12 December 2020

1 reference

12 December 2020

Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome

1 reference

12 December 2020

Therapeutic strategies for long-QT syndrome: does the molecular substrate matter?

1 reference

12 December 2020

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

1 reference

12 December 2020

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

1 reference

12 December 2020

Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells

1 reference

12 December 2020

Modelling the long QT syndrome with induced pluripotent stem cells

1 reference

12 December 2020

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

1 reference

12 December 2020

Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A

1 reference

12 December 2020

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

1 reference

12 December 2020

Mortality in Friedreich ataxia

1 reference

12 December 2020

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

1 reference

12 December 2020

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA).

1 reference

12 December 2020

Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations

1 reference

12 December 2020

Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification

1 reference

12 December 2020

Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation

1 reference

12 December 2020

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

1 reference

12 December 2020

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

1 reference

12 December 2020

In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells

1 reference

12 December 2020

Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming

1 reference

12 December 2020

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

1 reference

12 December 2020

Disease characterization using LQTS-specific induced pluripotent stem cells

1 reference

12 December 2020

Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells

1 reference

12 December 2020

Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy

1 reference

12 December 2020

Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

1 reference

12 December 2020

Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes

1 reference

12 December 2020

Hypertrophic cardiomyopathy: diagnosis, risk stratification and treatment

1 reference

12 December 2020

Genetic testing in heritable cardiac arrhythmia syndromes: differentiating pathogenic mutations from background genetic noise

1 reference

12 December 2020

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.

1 reference

12 December 2020

Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes

1 reference

12 December 2020

Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets

1 reference

12 December 2020

A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards

1 reference

12 December 2020

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

1 reference

12 December 2020

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

1 reference

12 December 2020

Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing.

1 reference

12 December 2020

Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs

1 reference

12 December 2020

Modeling of lamin A/C mutation premature cardiac aging using patient‐specific induced pluripotent stem cells

1 reference

12 December 2020

In vivo differentiation of induced pluripotent stem cell-derived cardiomyocytes

1 reference

12 December 2020

Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture

1 reference

12 December 2020

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity

1 reference

12 December 2020

Hepatogenesis of murine induced pluripotent stem cells in 3D micro-cavitary hydrogel system for liver regeneration.

1 reference

12 December 2020

Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype

1 reference

12 December 2020

Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: risk stratification of perinatal long-QT syndrome

1 reference

12 December 2020

Modeling type 3 long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem cells

1 reference

12 December 2020

Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays

1 reference

12 December 2020

Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells

1 reference

12 December 2020

Patient-specific stem cells and cardiovascular drug discovery

1 reference

12 December 2020

The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

1 reference

12 December 2020

Identifiers

DOI

10.1253/CIRCJ.CJ-14-0182

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json

14 May 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6530482&resulttype=core&format=json