(Q24654761)

0 references

L J Gray

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A J G Bath

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T Miyata

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A R Green

British Journal of Pharmacology

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language of work or name

English

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publication date

August 2009

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published in

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volume

157

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issue

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page(s)

1157-71

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cites work

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On the Analysis and Interpretation of Outcome Measures in Stroke Clinical Trials: Lessons From the SAINT I Study of NXY-059 for Acute Ischemic Stroke

7 April 2017

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NXY-059 for acute ischemic stroke

7 April 2017

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Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

7 April 2017

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Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality

7 April 2017

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Pharmacological approaches to acute ischaemic stroke: reperfusion certainly, neuroprotection possibly

28 September 2017

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Progesterone for the treatment of experimental brain injury; a systematic review

28 September 2017

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Estrogens and experimental ischemic stroke: a systematic review

28 September 2017

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Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: a systematic review.

28 September 2017

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A systematic review of nitric oxide donors and L-arginine in experimental stroke; effects on infarct size and cerebral blood flow.

28 September 2017

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Systematic review and metaanalysis of the efficacy of FK506 in experimental stroke

28 September 2017

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NXY-059: a neuroprotective agent in acute stroke

28 September 2017

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Allocation concealment in randomised trials: defending against deciphering

28 September 2017

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Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke

28 September 2017

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Recommendations for standards regarding preclinical neuroprotective and restorative drug development

28 September 2017

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Meta-analysis of the literature or of individual patient data: is there a difference?

28 September 2017

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Investigating the free radical trapping ability of NXY-059, S-PBN and PBN.

28 September 2017

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Pharmacokinetics in renally impaired subjects of NXY-059, a nitrone-based, free-radical trapping agent developed for the treatment of acute stroke

30 May 2018

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

30 May 2018

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NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species

30 May 2018

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Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.

21 January 2018

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NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials

21 January 2018

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Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.

28 November 2018

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A novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia

28 November 2018

1 reference

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Pharmacokinetics of NXY-059, a nitrone-based free radical trapping agent, in healthy young and elderly subjects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial

28 November 2018

1 reference

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Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia

28 November 2018

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Nitrone derivatives of trolox as neuroprotective agents.

28 November 2018

1 reference

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Coadministration of NXY-059 and tenecteplase six hours following embolic strokes in rabbits improves clinical rating scores

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Tolerability of NXY-059 at higher target concentrations in patients with acute stroke

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059 maintains Akt activation and inhibits release of cytochrome C after focal cerebral ischemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Effects of the spin trap agent disodium- [tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit Large clot embolic stroke model: combination studies with tissue plasminogen activator

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059 for the treatment of acute ischemic stroke

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19422398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Can We Improve the Statistical Analysis of Stroke Trials?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19422398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2009.00196.X

1 reference

1 reference

1 reference

PubMed publication ID

19422398

1 reference