(Q24564216)

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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

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title

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection (English)

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B N Ames

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author name string

W E Durston

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E Yamasaki

series ordinal

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F D Lee

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language of work or name

English

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publication date

August 1973

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published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

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issue

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page(s)

2281-5

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cites work

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

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PubMed Central

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Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

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Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. II. Role of the cytochrome P-450 and P-448 fractions in drug and steroid hydroxylations

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24 March 2017

Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

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Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo

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30 May 2018

A microbial assay for detecting chemical mutagens in tissue homogenates

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30 May 2018

Rapid detection of mutagens and carcinogens.

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30 May 2018

Frameshift mutagenesis in Salmonella.

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30 May 2018

Antitumor and mutagenic properties of a variety of heterocyclic nitrogen and sulfur mustards

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30 May 2018

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

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Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.

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Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes.

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The effect of oral phenobarbitone on hepatic microsomal cytochrome P-450 and demethylation activity in rats fed normal and low protein diets

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Oxidation and protein binding of aromatic amines by rat liver microsomes

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Molecular Basis of a Mutational Hot Spot in the Lysozyme Gene of Bacteriophage T4

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Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

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K-region epoxides of polycyclic hydrocarbons: reactions with nucleic acids and polyribonucleotides

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/4151811

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.70.8.2281

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1478874

ADS bibcode

1973PNAS...70.2281A

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OpenCitations bibliographic resource ID

1478874

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1478874

PubMed publication ID

4151811

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1478874

ResearchGate publication ID

19013577

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