(Q24291065)

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X Zhang

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A A Fedorov

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S G Nathenson

CTLA-4 and T cell activation

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language of work or name

English

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publication date

29 March 2001

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published in

Nature

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volume

410

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issue

6828

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page(s)

604-8

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cites work

1 reference

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CTLA4-Ig: a novel immunosuppressive agent

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Structural analysis of CTLA-4 function in vivo

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Structure of murine CTLA-4 and its role in modulating T cell responsiveness

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Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

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Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

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Structural basis of cell-cell adhesion by cadherins

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Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28

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Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

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Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis

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[25] Protein multiple sequence alignment and flexible pattern matching

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