(Q24290845)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0001621

Purinergic receptor P2Y12

1 reference

GOA release 2020-03-11

hemostasis

1 reference

GOA release 2020-03-11

D Julius

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author name string

G Hollopeter

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H M Jantzen

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D Vincent

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G Li

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L England

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V Ramakrishnan

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R B Yang

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P Nurden

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A Nurden

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P B Conley

Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

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language of work or name

English

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publication date

11 January 2001

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published in

Nature

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volume

409

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issue

6817

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page(s)

202-7

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cites work

1 reference

7 January 2021

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice

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7 January 2021

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.

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7 January 2021

The thienopyridine ticlopidine selectively prevents the inhibitory effects of ADP but not of adrenaline on cAMP levels raised by stimulation of the adenylate cyclase of human platelets by PGE1.

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7 January 2021

Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase

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7 January 2021

FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors

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7 January 2021

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function

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7 January 2021

G beta gamma binds directly to the G protein-gated K+ channel, IKACh

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7 January 2021

The human platelet ADP receptor activates Gi2 proteins

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7 January 2021

2-Methylthioadenosine[beta-32P]diphosphate. An agonist and radioligand for the receptor that inhibits the accumulation of cyclic AMP in intact blood platelets

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7 January 2021

Receptors for ADP on human blood platelets.

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7 January 2021

The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists

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7 January 2021

An STS-based radiation hybrid map of the human genome

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7 January 2021

A G protein-coupled receptor for UDP-glucose

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7 January 2021

ADP receptors and clinical bleeding disorders

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7 January 2021

ADP can induce aggregation of human platelets via both P2Y(1) and P(2T) receptors

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7 January 2021

The P2Y1 receptor, necessary but not sufficient to support full ADP-induced platelet aggregation, is not the target of the drug clopidogrel

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7 January 2021

Ultrastructural studies of platelet aggregates from human subjects receiving clopidogrel and from a patient with an inherited defect of an ADP-dependent pathway of platelet activation

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7 January 2021

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1 reference

7 January 2021