(Q22254722)

English

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

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CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells (English)

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Alzheimer's disease

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based on heuristic

inferred from title

CLN3 lysosomal/endosomal transmembrane protein, battenin

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GOA release 2020-03-11

regulation of protein processing

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GOA release 2020-03-11

author name string

A A Golabek

1

author given names

A A

author last names

Golabek

1 reference

PubMed publication ID

28 March 2023

E Kida

2

author given names

E

author last names

Kida

1 reference

PubMed publication ID

28 March 2023

M Walus

3

author given names

M

author last names

Walus

1 reference

PubMed publication ID

28 March 2023

W Kaczmarski

4

author given names

W

author last names

Kaczmarski

1 reference

PubMed publication ID

28 March 2023

M Michalewski

5

author given names

M

author last names

Michalewski

1 reference

PubMed publication ID

28 March 2023

K E Wisniewski

6

author given names

K E

author last names

Wisniewski

1 reference

PubMed publication ID

28 March 2023

language of work or name

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publication date

July 2000

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Molecular Genetics and Metabolism

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70

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3

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203-13

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Variability in the clinical and pathological findings in the neuronal ceroid lipofuscinoses: Review of data and observations

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease)

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Phagosomal pH determination by dual fluorescence flow cytometry

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for phosphorylation of CLN3 protein associated with Batten disease.

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

The subcellular location of the yeast Saccharomyces cerevisiae homologue of the protein defective in the juvenile form of Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific mannose-6-phosphate receptor-independent sorting of pro-cathepsin D in breast cancer cells

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Reevaluation of neuronal ceroid lipofuscinoses: atypical juvenile onset may be the result of CLN2 mutations.

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression studies of CLN3 protein (battenin) in fusion with the green fluorescent protein in mammalian cells in vitro

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of intracellular distribution and trafficking of the CLN3 protein in fusion with the green fluorescent protein in vitro

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Topographic heterogeneity of amyloid B-protein epitopes in brains with various forms of neuronal ceroid lipofuscinoses suggesting defective processing of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease Consortium

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of a novel gene underlying batten disease, CLN3

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered amyloid beta-protein precursor processing in brains of patients with neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated lysosomal pH in Mucolipidosis type IV cells

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

A model for Batten disease protein CLN3: functional implications from homology and mutations

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure, function and regulation of the vacuolar (H+)-ATPases

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific alterations in levels of mannose 6-phosphorylated glycoproteins in different neuronal ceroid lipofuscinoses

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression studies of CLN3 protein.

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Light and electron microscopic studies on subunit c in cultured fibroblasts in late infantile and juvenile Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

A yeast model for the study of Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotypic reversal of the btn1 defects in yeast by chloroquine: a yeast model for Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

The vacuolar H(+)-ATPase inhibitor bafilomycin A1 differentially affects proteolytic processing of mutant and wild-type beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Lysosomal targeting of palmitoyl-protein thioesterase

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Biosynthesis and transport of cathepsin D in cultured human fibroblasts

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective intracellular transport of CLN3 is the molecular basis of Batten disease (JNCL)

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of where and which types of proteinases participate in lysosomal proteinase processing using bafilomycin A1 and Helicobacter pylori Vac A toxin

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

Presidential address: Studies in the neuronal ceroid-lipofuscinoses

1 reference

https://api.crossref.org/works/10.1006%2FMGME.2000.3006

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1006/MGME.2000.3006

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