(Q21989344)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48725

Pericentrin/AKAP-450 centrosomal targeting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

protein binding

5 references

9 May 2019

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

ciliary basal body

centrosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 references

9 May 2019

9 May 2019

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Large-scale identification of mammalian proteins localized to nuclear sub-compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

pericentriolar material

1 reference

9 May 2019

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

cis-Golgi network

1 reference

9 May 2019

Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

centriolar satellite

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

3 references

9 May 2019

9 May 2019

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

intercellular bridge

1 reference

9 May 2019

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

centriole

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

9 May 2019

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

motile cilium

1 reference

9 May 2019

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

microtubule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

positive regulation of intracellular protein transport

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

limb morphogenesis

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

kidney development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

multicellular organism growth

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

mitotic spindle organization

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

head development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

negative regulation of apoptotic process

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

neuron migration

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

in utero embryonic development

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

embryonic heart tube development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

vasculature development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

spindle organization

1 reference

9 May 2019

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

embryonic brain development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

cerebellar cortex morphogenesis

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

neural precursor cell proliferation

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

camera-type eye development

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

olfactory bulb development

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

microtubule cytoskeleton organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

brain morphogenesis

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

cilium assembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

1 reference

9 May 2019

Pericentrin/AKAP-450 centrosomal targeting domain

has part(s)

1 reference

InterPro Release 71.0