(Q21981482)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99J83

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

protein binding

5 references

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

phagophore assembly site membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99J83&geneProductId=UniProtKB:Q99J83

3 references

16 July 2018

16 July 2018

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99J83&geneProductId=UniProtKB:Q99J83

16 July 2018

Autophagosomes form at ER-mitochondria contact sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99J83&geneProductId=UniProtKB:Q99J83

mitochondria associated membranes

1 reference

14 February 2019

Autophagosomes form at ER-mitochondria contact sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

1 reference

14 February 2019

TAS

membrane

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

Atg12-Atg5-Atg16 complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

axoneme

1 reference

14 February 2019

Functional interaction between autophagy and ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

autophagosome

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

phagophore assembly site membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

4 references

14 February 2019

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Autophagosomes form at ER-mitochondria contact sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

protein lipidation involved in autophagosome assembly

biological process

1 reference

14 February 2019

Epigenetic regulation of autophagy by the methyltransferase G9a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

negative regulation of histone H4-K16 acetylation

1 reference

14 February 2019

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

negative regulation of phagocytosis

1 reference

14 February 2019

Autophagy regulates phagocytosis by modulating the expression of scavenger receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

1 reference

14 February 2019

post-translational protein modification

1 reference

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

regulation of release of sequestered calcium ion into cytosol

1 reference

14 February 2019

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

cellular response to starvation

1 reference

14 February 2019

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

vasodilation

1 reference

14 February 2019

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

negative regulation of apoptotic process

cellular homeostasis

1 reference

14 February 2019

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

otolith development

1 reference

14 February 2019

Autophagy is essential for mouse sense of balance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

regulation of reactive oxygen species metabolic process

1 reference

14 February 2019

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

autophagosome assembly

negative thymic T cell selection

IGI

negative regulation of protein ubiquitination

1 reference

14 February 2019

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

blood vessel remodeling

1 reference

14 February 2019

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

response to fungus

1 reference

14 February 2019

Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

negative regulation of reactive oxygen species metabolic process

1 reference

14 February 2019

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

negative stranded viral RNA replication

1 reference

14 February 2019

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

autophagy of nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99J83&geneProductId=UniProtKB:Q99J83

1 reference

16 July 2018

heart contraction

1 reference

14 February 2019

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

positive regulation of mucus secretion

1 reference

14 February 2019

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

cellular response to nitrosative stress

1 reference

14 February 2019

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

ventricular cardiac muscle cell development

1 reference

14 February 2019

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

antigen processing and presentation of endogenous antigen

IGI

cellular response to nitrogen starvation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

1 reference

14 February 2019

autophagy of mitochondrion

1 reference

16 July 2018

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99J83&geneProductId=UniProtKB:Q99J83

aggrephagy

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

ISO

14 February 2019

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

macroautophagy

4 references

14 February 2019

Autophagy regulates phagocytosis by modulating the expression of scavenger receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

7 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

ISO

14 February 2019

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

autophagosome assembly

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83

C-terminal protein lipidation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99J83