(Q21496347)

Moesin tail domain superfamily

1 reference

FERM/acyl-CoA-binding protein superfamily

1 reference

PH-like domain superfamily

1 reference

FERM superfamily, second domain

1 reference

Ezrin/radixin/moesin

1 reference

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.25.1.1

2 October 2019

hierarchical database ID heuristic

membrane protein

1 reference

inferred from GOA cell component → membrane

Band 4.1 domain, protein family

1 reference

FERM central domain, protein family

1 reference

FERM, C-terminal PH-like domain, protein family

1 reference

FERM, N-terminal domain, protein family

1 reference

FERM domain, protein family

1 reference

FERM conserved site, protein family

1 reference

cytoskeletal protein binding

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

1 reference

14 February 2019

actin filament binding

5 references

14 February 2019

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

cell adhesion molecule binding

protein C-terminus binding

1 reference

14 February 2019

Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

disordered domain specific binding

1 reference

14 February 2019

Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

cadherin binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26040&geneProductId=UniProtKB:P26040

cell component

cytoplasm

ruffle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

1 reference

14 February 2019

actin cytoskeleton

myelin sheath

1 reference

7 November 2018

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26040&geneProductId=UniProtKB:P26040

microvillus

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Cdx2 regulates endo-lysosomal function and epithelial cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

apical plasma membrane

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Foxj1 is required for apical localization of ezrin in airway epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

ciliary basal body

1 reference

14 February 2019

Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

plasma membrane

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

apical part of cell

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

14 February 2019

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

intracellular anatomical structure

1 reference

24 April 2018

CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26040&geneProductId=UniProtKB:P26040

cell cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

1 reference

14 February 2019

brush border

actin filament

ISS

extrinsic component of membrane

1 reference

14 February 2019

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

1 reference

14 February 2019

basolateral plasma membrane

myelin sheath

HDA

1 reference

14 February 2019

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

leukocyte cell-cell adhesion

HDA

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

actin filament bundle assembly

ISS

positive regulation of multicellular organism growth

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

microvillus assembly

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

intestinal D-glucose absorption

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

establishment or maintenance of apical/basal cell polarity

1 reference

14 February 2019

Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

epithelial cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

regulation of cell shape

membrane to membrane docking

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

regulation of microvillus length

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

receptor internalization

1 reference

14 February 2019

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

terminal web assembly

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

positive regulation of protein localization to plasma membrane

1 reference

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26040

1 reference

FERM conserved site

1 reference

FERM, C-terminal PH-like domain

1 reference

FERM central domain

1 reference

FERM, N-terminal

1 reference

Band 4.1 domain

1 reference

Transporter Classification Database ID

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

8.A.25.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database