(Q21495778)

ionotropic glutamate receptor, metazoa

1 reference

Receptor, ligand binding region, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ionotropic glutamate receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

AMPA glutamate receptor activity

5 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

12 references

9 August 2016

retrieved

8 April 2019

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Molecular constituents of neuronal AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Proteomics analysis of immuno-precipitated synaptic protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

extracellularly glutamate-gated ion channel activity

IPI

1 reference

9 August 2016

ionotropic glutamate receptor activity

1 reference

9 August 2016

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

G-protein alpha-subunit binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

protein C-terminus binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

adenylate cyclase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

protein domain specific binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

G-protein beta-subunit binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

beta-2 adrenergic receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

identical protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

protein kinase A binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

scaffold protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

IBA

IMP

3 references

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

EXP

immunoglobulin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

integral component of membrane

cell component

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

3 references

postsynaptic membrane

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

endoplasmic reticulum membrane

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

4 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

4 references

9 August 2016

retrieved

8 April 2019

Control of excitatory and inhibitory synapse formation by neuroligins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

3 references

9 August 2016

retrieved

8 April 2019

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

1 reference

9 August 2016

endoplasmic reticulum

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

AMPA glutamate receptor complex

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

LTP requires a unique postsynaptic SNARE fusion machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

IDA

neuromuscular junction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

early endosome membrane

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

AMPA glutamate receptor complex

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Molecular constituents of neuronal AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

protein-containing complex

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

somatodendritic compartment

1 reference

8 April 2019

Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

recycling endosome membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

Superresolution imaging of chemical synapses in the brain

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

postsynaptic density membrane

IDA

1 reference

8 April 2019

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

IDA

glutamatergic synapse

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Regulation of hippocampal synaptic strength by glial xCT.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

integral component of postsynaptic membrane

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

integral component of presynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

integral component of postsynaptic density membrane

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

8 April 2019

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

3 references

ion transmembrane transport

2 references

9 August 2016

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

1 reference

9 August 2016

ionotropic glutamate receptor signaling pathway

2 references

9 August 2016

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

receptor internalization

1 reference

9 August 2016

1 reference

9 August 2016

regulation of receptor recycling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

response to toxic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

neuronal action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

positive regulation of membrane potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

regulation of synaptic plasticity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

modulation of chemical synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

positive regulation of synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

regulation of postsynaptic membrane potential

1 reference

8 April 2019

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

regulation of postsynaptic cytosolic calcium ion concentration

IMP

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23818

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain

has part(s)

1 reference

Ionotropic glutamate receptor domain

1 reference

Receptor, ligand binding region

1 reference