(Q21127167)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49459

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-conjugating enzyme, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

ubiquitin protein ligase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49459&geneProductId=UniProtKB:P49459

1 reference

27 February 2018

ubiquitin-protein transferase activity

protein binding

4 references

8 April 2019

WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

ATP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

ubiquitin binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49459&geneProductId=UniProtKB:P49459

1 reference

7 November 2018

ubiquitin conjugating enzyme activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49459&geneProductId=UniProtKB:P49459

1 reference

27 February 2018

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

HULC complex

1 reference

27 February 2018

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49459&geneProductId=UniProtKB:P49459

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

XY body

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

histone H2A ubiquitination

biological process

1 reference

8 April 2019

Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

postreplication repair

1 reference

8 April 2019

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

protein polyubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49459&geneProductId=UniProtKB:P49459

1 reference

27 February 2018

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

protein K11-linked ubiquitination

1 reference

8 April 2019

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

protein K48-linked ubiquitination

1 reference

8 April 2019

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

positive regulation of cell population proliferation

1 reference

8 April 2019

Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

response to UV

IGI

1 reference

8 April 2019

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

proteasome-mediated ubiquitin-dependent protein catabolic process

IGI

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

protein autoubiquitination

1 reference

8 April 2019

Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

protein ubiquitination

in utero embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

maternal process involved in female pregnancy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

chromatin organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

1 reference

8 April 2019

DNA repair

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

blastocyst hatching

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49459

Ubiquitin-conjugating enzyme E2

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49459

Ubiquitin-conjugating enzyme, active site

1 reference

InterPro Release 71.0