(Q21124363)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62834

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62834

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

protein-containing complex binding

3 references

17 October 2017

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834

17 October 2017

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834

9 May 2019

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

GTP binding

protein binding

9 references

9 May 2019

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Ras/Rap effector specificity determined by charge reversal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

GTPase activity

GTPase activity

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

GDP binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

cell component

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

myelin sheath

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834

plasma membrane

guanyl-nucleotide exchange factor complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

neuron projection

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

extracellular exosome

early endosome

ISS

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

cell junction

perinuclear region of cytoplasm

ISS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

3 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

specific granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

phagocytic vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

extracellular exosome

HDA

1 reference

9 May 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

HDA

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

establishment of endothelial barrier

biological process

1 reference

9 May 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

positive regulation of glucose import

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

microvillus assembly

1 reference

9 May 2019

Rap2A links intestinal cell polarity to brush border formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

regulation of cell junction assembly

1 reference

9 May 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

regulation of insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

small GTPase mediated signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

Rap protein signal transduction

1 reference

17 October 2017

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834

cellular response to organic cyclic compound

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

negative regulation of synaptic vesicle exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

liver regeneration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

protein transport

1 reference

1 January 2018

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

response to antineoplastic agent

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

response to carbohydrate

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

negative regulation of collagen biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

cellular response to glucose stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

1 reference

9 May 2019

protein localization to plasma membrane

1 reference

9 May 2019

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

Rap protein signal transduction

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

cellular response to cAMP

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834

small GTP-binding protein domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62834

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016