(Q21119246)

Protein kinase-like domain superfamily

1 reference

Protein kinase, C-terminal domain, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

MSK2, N-terminal catalytic domain, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

protein serine/threonine kinase activity

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

27 March 2018

27 March 2018

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

ribosomal protein S6 kinase activity

NAS

1 reference

8 April 2019

C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

NAS

protein binding

3 references

8 April 2019

The protein interaction landscape of the human CMGC kinase group

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

ATP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

magnesium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

protein serine/threonine kinase activity

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

cell component

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

3 references

27 March 2018

27 March 2018

C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB)

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

27 March 2018

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75676&geneProductId=UniProtKB:O75676

cytoplasm

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

4 references

8 April 2019

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

regulation of transcription, DNA-templated

biological process

1 reference

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

positive regulation of histone acetylation

1 reference

8 April 2019

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

interleukin-1-mediated signaling pathway

1 reference

8 April 2019

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

positive regulation of CREB transcription factor activity

1 reference

8 April 2019

MSK activation and physiological roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

positive regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

MSK activation and physiological roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

1 reference

8 April 2019

negative regulation of cytokine production

1 reference

8 April 2019

MSK activation and physiological roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

3 references

8 April 2019

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

intracellular signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

3 references

8 April 2019

8 April 2019

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75676

has part(s)

AGC-kinase, C-terminal

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

protein kinase, C-terminal

1 reference

serine/threonine-protein kinase, active site

1 reference

MSK2, N-terminal catalytic domain

1 reference