(Q21118740)

C-type lectin fold

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

Natural killer cell receptor-like, C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein homodimerization activity

1 reference

9 May 2019

Regulation of cutaneous malignancy by gammadelta T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

1 reference

24 April 2018

A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

3 references

9 May 2019

Four novel ULBP splice variants are ligands for human NKG2D.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Regulation of cutaneous malignancy by gammadelta T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

MHC class Ib receptor activity

IPI

1 reference

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

MHC class I protein binding

IMP

1 reference

9 May 2019

Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

signaling receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

4 references

14 February 2019

Four novel ULBP splice variants are ligands for human NKG2D.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

Regulation of cutaneous malignancy by gammadelta T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

integral component of membrane

IBA

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

external side of plasma membrane

5 references

24 April 2018

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

24 April 2018

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

24 April 2018

Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

24 April 2018

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

24 April 2018

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54709&geneProductId=UniProtKB:O54709

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

Regulation of cutaneous malignancy by gammadelta T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

external side of plasma membrane

6 references

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Regulation of cutaneous malignancy by gammadelta T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

adaptive immune response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

immune system process

1 reference

9 May 2019

positive regulation of nitric oxide biosynthetic process

1 reference

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

negative regulation of natural killer cell chemotaxis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of interferon-gamma production

1 reference

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

stimulatory C-type lectin receptor signaling pathway

1 reference

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

negative regulation of GTPase activity

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

cellular response to lipopolysaccharide

1 reference

9 May 2019

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of natural killer cell mediated cytotoxicity

3 references

14 February 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

14 February 2019

A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

defense response to Gram-positive bacterium

1 reference

9 May 2019

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

natural killer cell mediated cytotoxicity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

innate immune response

1 reference

9 May 2019

natural killer cell activation

1 reference

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of myeloid dendritic cell activation

ISO

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of apoptotic process

ISO

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

positive regulation of natural killer cell mediated cytotoxicity

ISO

5 references

9 May 2019

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54709

C-type lectin-like domain

IBA

has part(s)

1 reference

Natural killer cell receptor-like, C-type lectin-like domain

1 reference