(Q21118434)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62318

Small nuclear ribonucleoprotein Sm D3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62318

LSM domain, eukaryotic/archaea-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

17 October 2017

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

protein binding

9 references

8 April 2019

Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

A protein interaction framework for human mRNA degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

enzyme binding

1 reference

8 April 2019

Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U7 snRNA binding

1 reference

8 April 2019

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

telomerase RNA binding

1 reference

8 April 2019

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U1 snRNP binding

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

RNA binding

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

17 October 2017

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

RNA binding

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

HDA

cell component

SMN-Sm protein complex

1 reference

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

prespliceosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

1 reference

17 October 2017

catalytic step 2 spliceosome

1 reference

17 October 2017

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

spliceosomal tri-snRNP complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

1 reference

17 October 2017

U5 snRNP

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U12-type spliceosomal complex

1 reference

17 October 2017

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

U2 snRNP

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

methylosome

1 reference

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U7 snRNP

1 reference

8 April 2019

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

precatalytic spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

1 reference

17 October 2017

small nuclear ribonucleoprotein complex

1 reference

8 April 2019

Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

pICln-Sm protein complex

1 reference

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

telomerase holoenzyme complex

1 reference

8 April 2019

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

spliceosomal complex

cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

commitment complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U4 snRNP

1 reference

17 October 2017

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

extracellular exosome

1 reference

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

nuclear body

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

3 references

8 April 2019

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U1 snRNP

Ensembl genome database project

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Functional organization of the Sm core in the crystal structure of human U1 snRNP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U12-type spliceosomal complex

U4/U6 x U5 tri-snRNP complex

1 reference

8 April 2019

Molecular architecture of the human U4/U6.U5 tri-snRNP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U2-type precatalytic spliceosome

1 reference

8 April 2019

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

U2-type catalytic step 2 spliceosome

1 reference

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

catalytic step 2 spliceosome

termination of RNA polymerase II transcription

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

RNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

mRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

spliceosomal complex assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

1 reference

17 October 2017

histone mRNA metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

protein methylation

1 reference

8 April 2019

Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

import into nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

1 reference

8 April 2019

spliceosomal snRNP assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

17 October 2017

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62318&geneProductId=UniProtKB:P62318

spliceosomal snRNP assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

mRNA splicing, via spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

3 references

8 April 2019

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62318

LSM domain, eukaryotic/archaea-type

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62318

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016