(Q21114013)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20138

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20138

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Immunoglobulin domain, protein family

1 reference

image

CD33 protein.png
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0 references

1 reference

13 November 2019

1 reference

13 November 2019

5 references

9 May 2019

Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphorylation, and the tyrosine phosphatases, Shp1 and Shp2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

The sialoadhesin CD33 is a myeloid-specific inhibitory receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

carbohydrate binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

signaling receptor activity

1 reference

9 May 2019

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

protein phosphatase binding

1 reference

9 May 2019

Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

sialic acid binding

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

integral component of plasma membrane

1 reference

9 May 2019

Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

external side of plasma membrane

1 reference

9 May 2019

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

5 references

9 May 2019

9 May 2019

Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

9 May 2019

9 May 2019

Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

specific granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

tertiary granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

peroxisome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

Golgi apparatus

1 reference

9 May 2019

Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

biological process

cell-cell signaling

1 reference

9 May 2019

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

signal transduction

1 reference

9 May 2019

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of cell population proliferation

1 reference

9 May 2019

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

regulation of immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

1 reference

9 May 2019

immune response-inhibiting signal transduction

1 reference

9 May 2019

Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

positive regulation of protein secretion

1 reference

9 May 2019

FRMD4A-cytohesin signaling modulates the cellular release of tau.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of interleukin-1 beta production

1 reference

9 May 2019

Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of interleukin-8 production

1 reference

9 May 2019

Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of tumor necrosis factor production

1 reference

9 May 2019

Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of calcium ion transport

1 reference

9 May 2019

The sialoadhesin CD33 is a myeloid-specific inhibitory receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

positive regulation of protein tyrosine phosphatase activity

1 reference

9 May 2019

The sialoadhesin CD33 is a myeloid-specific inhibitory receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

negative regulation of monocyte activation

1 reference

9 May 2019

Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20138

physically interacts with

Tenomodulin

two-hybrid screening

1 reference

A reference map of the human binary protein interactome

16 June 2020

http://www.interactome-atlas.org/download

Thrombospondin type 1 domain containing 7A

0 references

Stearoyl-CoA desaturase

https://docs.openalex.org/download-snapshot/snapshot-data-format

two-hybrid screening

0 references

cytochrome b5 type B

0 references

Emerin

0 references

Identifiers

MeSH descriptor ID

D063268

subject named as

Sialic Acid Binding Ig-like Lectin 3

0 references

MeSH tree code

D12.776.503.921.400

0 references

D23.050.301.264.900.565

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023