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(Q21112003)
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SAS-6 centriolar assembly protein
mammalian protein found in Homo sapiens
spindle assembly abnormal protein 6 homolog
SASS6
In more languages
default values for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6UVJ0
part of
SAS-6, N-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6UVJ0
Spindle assembly abnormal protein 6, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6UVJ0
encoded by
SASS6
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6UVJ0
molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IPI
retrieved
8 April 2019
stated in
Nucleoporin Nup62 maintains centrosome homeostasis
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IPI
retrieved
8 April 2019
stated in
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IPI
retrieved
8 April 2019
stated in
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IPI
retrieved
8 April 2019
stated in
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IPI
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
centriole
determination method
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
retrieved
8 April 2019
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
STIL is required for centriole duplication in human cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
deuterosome
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
microtubule organizing center
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
centrosome
determination method
IDA
NAS
5 references
retrieved
8 April 2019
stated in
Proteomic characterization of the human centrosome by protein correlation profiling
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
NAS
retrieved
8 April 2019
stated in
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
Nucleoporin Nup62 maintains centrosome homeostasis
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
retrieved
8 April 2019
stated in
STIL is required for centriole duplication in human cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IDA
biological process
cell cycle
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IEA
centriole replication
determination method
IMP
3 references
retrieved
8 April 2019
stated in
The Polo kinase Plk4 functions in centriole duplication
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IMP
retrieved
8 April 2019
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IMP
retrieved
8 April 2019
stated in
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IMP
centrosome duplication
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells
GOA
curator
UniProt
UniProt protein ID
Q6UVJ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6UVJ0
determination method
IMP
has part(s)
Spindle assembly abnormal protein 6, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6UVJ0
Identifiers
RefSeq protein ID
NP_001291758
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
163786
NP_919268
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
163786
XP_016855975
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
163786
UniProt protein ID
Q6UVJ0
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6UVJ0
Ensembl protein ID
ENSP00000287482
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000287482
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