(Q21100520)

English

Caspase recruitment domain family member 18

mammalian protein found in Homo sapiens

ICEBERG caspase-1 inhibitor
CARD18
caspase recruitment domain-containing protein 18
caspase-1 inhibitor Iceberg

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Statements

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

peptidase inhibitor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

cysteine-type endopeptidase inhibitor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

cysteine-type endopeptidase activity involved in execution phase of apoptosis

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730

determination method or standard

IBA

protein binding

determination method or standard

IPI

3 references

retrieved

8 April 2019

stated in

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IPI

retrieved

8 April 2019

stated in

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IPI

retrieved

8 April 2019

stated in

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IPI

caspase binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IPI

CARD domain binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IPI

cysteine-type endopeptidase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730

determination method or standard

IBA

protein-containing complex

determination method or standard

IDA

3 references

retrieved

8 April 2019

stated in

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IDA

retrieved

8 April 2019

stated in

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IDA

retrieved

8 April 2019

stated in

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IDA

biological process

negative regulation of peptidase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

regulation of apoptotic process

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

inflammatory response

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

ICEBERG: a novel inhibitor of interleukin-1beta generation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

NAS

execution phase of apoptosis

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730

determination method or standard

IBA

negative regulation of protein binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IDA

inhibition of cysteine-type endopeptidase activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IDA

proteolysis

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730

determination method or standard

IEA

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

21 March 2016

language of work or name

English

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