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(Q21095261)

English

PERK-mediated unfolded protein response

A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular pr

  • endoplasmic reticulum unfolded protein response; PERK signaling
  • UPR signaling by PERK stress sensor
  • PERK branch of UPR
  • PKR-like ER kinase signal transduction
  • GO:0036499
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