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English
Cripto, FRL-1, cryptic family 1
mammalian protein found in Mus musculus
uniprot:P97766
cryptic protein
Cfc1
In more languages
default values for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P97766
part of
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Cryptic/Cripto, CFC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P97766
encoded by
Cfc1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P97766
molecular function
activin receptor binding
determination method
IPI
1 reference
retrieved
27 March 2018
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IPI
nodal binding
determination method
ISO
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
ISO
signaling receptor binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
nodal binding
determination method
IBA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
activin receptor binding
determination method
IBA
IPI
2 references
retrieved
14 February 2019
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IPI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
cell component
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
plasma membrane
determination method
IEA
TAS
2 references
retrieved
14 February 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
extracellular region
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IEA
anchored component of membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
extracellular region
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
cell surface
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
biological process
left lung morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
endoderm development
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IGI
anatomical structure development
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IGI
heart morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
spleen development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
post-embryonic development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
coronary vasculature development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
BMP signaling pathway
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IDA
nodal signaling pathway
determination method
IMP
1 reference
retrieved
27 March 2018
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
heart looping
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
atrial septum morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
determination of left/right symmetry
determination method
IMP
2 references
retrieved
27 March 2018
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IMP
retrieved
27 March 2018
stated in
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IMP
gastrulation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IEA
respiratory system development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
canonical Wnt signaling pathway
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IDA
liver development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
anterior/posterior pattern specification
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P97766&geneProductId=UniProtKB:P97766
determination method
IGI
digestive tract morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
determination of left/right symmetry
determination method
IBA
IMP
3 references
retrieved
14 February 2019
stated in
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
retrieved
14 February 2019
stated in
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
heart development
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
anterior/posterior pattern specification
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
BMP signaling pathway
determination method
IBA
IDA
2 references
retrieved
14 February 2019
stated in
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
nodal signaling pathway
determination method
IBA
IMP
2 references
retrieved
14 February 2019
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P97766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IMP
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
anatomical structure development
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97766
determination method
IBA
has part(s)
EGF-like, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P97766
EGF-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P97766
Cryptic/Cripto, CFC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P97766
Identifiers
RefSeq protein ID
NP_031711
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
12627
UniProt protein ID
P97766
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P97766
Ensembl protein ID
ENSMUSP00000027298
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000027298
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Wikiquote
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(0 entries)
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(0 entries)
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Multilingual sites
(0 entries)
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