(Q14907735)

DNA recombination/repair protein Rad51

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

AAA proteins

1 reference

DNA recombination and repair protein RecA, monomer-monomer interface, protein family

1 reference

Rad51/DMC1/RadA, protein family

1 reference

DNA recombination and repair protein RecA-like, ATP-binding domain, protein family

1 reference

DNA recombination and repair protein Rad51-like, C-terminal domain, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

10 September 2018

FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

single-stranded DNA binding

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

27 March 2018

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

protein binding

5 references

14 February 2019

Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

four-way junction DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

1 reference

27 March 2018

endodeoxyribonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

1 reference

27 March 2018

ATP binding

Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

double-stranded DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

protein C-terminus binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

identical protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

DNA polymerase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

single-stranded DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

enzyme binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cell component

cytoplasm

ISS

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

condensed nuclear chromosome

9 references

27 March 2018

Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Meiosis in mice without a synaptonemal complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

27 March 2018

Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

mitochondrial matrix

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

perinuclear region of cytoplasm

1 reference

14 February 2019

Rad51 expression and localization in B cells carrying out class switch recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

condensed chromosome

5 references

14 February 2019

Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Meiotic arrest and aneuploidy in MLH3-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase III beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

8 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Rad51 expression and localization in B cells carrying out class switch recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Disruption of CHTF18 causes defective meiotic recombination in male mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

chromatin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

lateral element

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

nucleolus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cytosol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

PML body

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

site of double-strand break

1 reference

14 February 2019

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

condensed nuclear chromosome

FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice

10 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Meiosis in mice without a synaptonemal complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

regulation of protein phosphorylation

biological process

1 reference

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

response to ionizing radiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

1 reference

27 March 2018

telomere organization

1 reference

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

reciprocal meiotic recombination

1 reference

27 March 2018

Rad51 expression and localization in B cells carrying out class switch recombination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

DNA recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

strand invasion

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

response to organic cyclic compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

DNA metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

cellular response to alkaloid

1 reference

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cellular response to DNA damage stimulus

Rad51 expression and localization in B cells carrying out class switch recombination

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

telomere maintenance via recombination

1 reference

14 February 2019

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

telomere maintenance via telomere lengthening

1 reference

14 February 2019

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

double-strand break repair via homologous recombination

Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

meiosis I

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cellular response to gamma radiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

cellular response to cisplatin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

chromosome organization involved in meiotic cell cycle

1 reference

27 March 2018

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297

response to toxic substance

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

replication-born double-strand break repair via sister chromatid exchange

1 reference

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

DNA repair

Rad51 expression and localization in B cells carrying out class switch recombination

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

cellular response to hydroxyurea

1 reference

14 February 2019

RAD51 mutants cause replication defects and chromosomal instability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

mitotic recombination-dependent replication fork processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

1 reference

14 February 2019

response to X-ray

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

response to glucoside

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

DNA recombinase assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

3 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

positive regulation of DNA ligation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

protein homooligomerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

mitotic recombination

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297

reciprocal meiotic recombination

1 reference

DNA recombination and repair protein Rad51-like, C-terminal

1 reference

DNA recombination and repair protein RecA-like, ATP-binding domain

1 reference

DNA recombination and repair protein RecA, monomer-monomer interface

1 reference

Rad51/DMC1/RadA

1 reference