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(Q14907216)
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Interleukin 21
mammalian protein found in Mus musculus
interleukin-21
Il21
uniprot:Q9ES17
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default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9ES17
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q9ES17
part of
four-helical cytokine-like, core
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9ES17
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9ES17
encoded by
Il21
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9ES17
molecular function
cytokine activity
determination method or standard
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9ES17
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
interleukin-2 receptor binding
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
cytokine receptor binding
determination method or standard
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
retrieved
9 May 2019
stated in
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IDA
cell component
extracellular region
determination method or standard
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9ES17
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
extracellular space
determination method or standard
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9ES17
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
intracellular anatomical structure
determination method or standard
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES17&geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
biological process
positive regulation of natural killer cell cytokine production
determination method or standard
IDA
1 reference
retrieved
9 May 2019
stated in
IL-21 induces the functional maturation of murine NK cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IDA
positive regulation of natural killer cell differentiation
determination method or standard
IDA
1 reference
retrieved
9 May 2019
stated in
IL-21 induces the functional maturation of murine NK cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IDA
B cell apoptotic process
determination method or standard
NAS
1 reference
retrieved
9 May 2019
stated in
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
GOA
curator
UniProt
UniProt protein ID
Q9ES17
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
NAS
positive regulation of cytokine production
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of interleukin-10 production
determination method or standard
IDA
1 reference
retrieved
9 May 2019
stated in
IL-21 induces the functional maturation of murine NK cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IDA
positive regulation of B cell differentiation
determination method or standard
NAS
1 reference
retrieved
9 May 2019
stated in
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
GOA
curator
UniProt
UniProt protein ID
Q9ES17
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
NAS
cell maturation
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of B cell proliferation
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
immune response
determination method or standard
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
positive regulation of T cell proliferation
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of cell population proliferation
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of interleukin-17 production
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of natural killer cell mediated cytotoxicity
determination method or standard
IDA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
retrieved
9 May 2019
stated in
IL-21 induces the functional maturation of murine NK cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IDA
tyrosine phosphorylation of STAT protein
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
positive regulation of tyrosine phosphorylation of STAT protein
determination method or standard
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
ISO
regulation of signaling receptor activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES17
determination method or standard
IEA
Identifiers
RefSeq protein ID
NP_001277970
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
60505
NP_068554
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
60505
UniProt protein ID
Q9ES17
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9ES17
Ensembl protein ID
ENSMUSP00000029273
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000029273
ENSMUSP00000124668
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124668
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