(Q14904616)

English

Transforming growth factor, beta 1

mammalian protein found in Mus musculus

transforming growth factor beta-1
transforming growth factor beta-1 proprotein
Tgfb1
uniprot:P04202

In more languages

default for all languages

No label defined

No description defined

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Transforming growth factor beta-1 proprotein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04202

Cystine-knot cytokine

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04202

Transforming growth factor-beta, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TGF-beta, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Transforming growth factor beta, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

type II transforming growth factor beta receptor binding

determination method

4 references

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

type III transforming growth factor beta receptor binding

determination method

cytokine activity

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

transforming growth factor beta receptor binding

determination method

3 references

21 June 2018

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

antigen binding

determination method

type I transforming growth factor beta receptor binding

determination method

protein serine/threonine kinase activator activity

determination method

1 reference

21 June 2018

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

protein binding

determination method

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

extracellular region

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

determination method

determination method

extracellular space

determination method

5 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Murine pregnancy-specific glycoprotein 23 induces the proangiogenic factors transforming-growth factor beta 1 and vascular endothelial growth factor a in cell types involved in vascular remodeling in pregnancy

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

blood microparticle

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

extracellular matrix

determination method

5 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Colocalization of TGF-beta 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

biological process

positive regulation of histone deacetylation

determination method

2 references

21 June 2018

A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of transcription regulatory region DNA binding

determination method

skeletal system development

determination method

tolerance induction to self antigen

determination method

1 reference

21 June 2018

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of protein phosphorylation

determination method

endoderm development

determination method

1 reference

21 June 2018

Identification of two distinct functions for TGF-beta in early mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to cholesterol

determination method

ureteric bud development

determination method

1 reference

21 June 2018

Smad expression during kidney development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of MAP kinase activity

determination method

regulation of sodium ion transport

determination method

1 reference

21 June 2018

Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to progesterone

determination method

negative regulation of cell cycle

determination method

mammary gland development

determination method

1 reference

21 June 2018

Regulated expression and growth inhibitory effects of transforming growth factor-beta isoforms in mouse mammary gland development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

T cell homeostasis

determination method

1 reference

21 June 2018

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of ossification

determination method

1 reference

21 June 2018

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of hyaluronan biosynthetic process

determination method

T cell differentiation

determination method

1 reference

21 June 2018

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of blood vessel endothelial cell migration

determination method

negative regulation of epithelial cell proliferation

determination method

regulation of binding

determination method

1 reference

21 June 2018

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

animal organ morphogenesis

determination method

1 reference

21 June 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

inner ear development

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of macrophage cytokine production

determination method

cell population proliferation

determination method

3 references

21 June 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

transforming growth factor beta receptor signaling pathway

determination method

5 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

face morphogenesis

determination method

1 reference

21 June 2018

The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of cell population proliferation

determination method

5 references

21 June 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of receptor clustering

determination method

1 reference

21 June 2018

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of apoptotic process

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of collagen biosynthetic process

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cellular response to transforming growth factor beta stimulus

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

pathway-restricted SMAD protein phosphorylation

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of DNA binding

determination method

1 reference

21 June 2018

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of actin cytoskeleton reorganization

determination method

1 reference

21 June 2018

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of fat cell differentiation

determination method

positive regulation of protein metabolic process

determination method

cell-cell junction organization

determination method

negative regulation of myoblast differentiation

determination method

positive regulation of protein kinase B signaling

determination method

common-partner SMAD protein phosphorylation

determination method

regulation of MAPK cascade

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

SMAD protein signal transduction

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

epidermal growth factor receptor signaling pathway

determination method

negative regulation of blood vessel endothelial cell migration

determination method

positive regulation of protein dephosphorylation

determination method

extrinsic apoptotic signaling pathway

determination method

mitotic cell cycle checkpoint signaling

determination method

positive regulation of fibroblast proliferation

determination method

1 reference

21 June 2018

The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of cell differentiation

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of branching involved in mammary gland duct morphogenesis

determination method

1 reference

21 June 2018

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cell activation

determination method

1 reference

21 June 2018

mSmile is necessary for bronchial smooth muscle and alveolar myofibroblast development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of peptidyl-serine phosphorylation

determination method

negative regulation of T cell proliferation

determination method

1 reference

21 June 2018

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment

determination method

1 reference

21 June 2018

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of cell growth

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of chemotaxis

determination method

protein export from nucleus

determination method

regulation of protein import into nucleus

determination method

1 reference

21 June 2018

The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of protein import into nucleus

determination method

oligodendrocyte development

determination method

1 reference

21 June 2018

Mutation of pescadillo disrupts oligodendrocyte formation in zebrafish

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of interleukin-17 production

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

TGF-beta is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

inflammatory response

determination method

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of interleukin-17 production

determination method

1 reference

21 June 2018

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

lymph node development

determination method

1 reference

21 June 2018

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

T cell activation

determination method

Notch signaling pathway

determination method

1 reference

21 June 2018

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of protein phosphorylation

determination method

SMAD protein complex assembly

determination method

regulation of striated muscle tissue development

determination method

1 reference

21 June 2018

TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to vitamin D

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

chondrocyte differentiation

determination method

regulatory T cell differentiation

determination method

regulation of cartilage development

determination method

1 reference

21 June 2018

Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFbeta signals

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

branch elongation involved in mammary gland duct branching

determination method

1 reference

21 June 2018

Mammary gland development in transforming growth factor beta1 null mutant mice: systemic and epithelial effects

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

female pregnancy

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cellular response to organic cyclic compound

determination method

cellular calcium ion homeostasis

determination method

1 reference

21 June 2018

TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of transcription by RNA polymerase II

determination method

3 references

21 June 2018

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to glucose

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of epithelial to mesenchymal transition

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

mitigation of host defenses by virus

determination method

lens fiber cell differentiation

determination method

1 reference

21 June 2018

The anaphase-promoting complex coordinates initiation of lens differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

extracellular matrix assembly

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

ATP biosynthetic process

determination method

hematopoietic progenitor cell differentiation

determination method

regulation of interleukin-23 production

determination method

1 reference

21 June 2018

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of protein secretion

determination method

frontal suture morphogenesis

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

epithelial to mesenchymal transition

determination method

phosphate-containing compound metabolic process

determination method

regulation of gene expression

determination method

1 reference

21 June 2018

The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

determination method

1 reference

21 June 2018

TGF-beta is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to radiation

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

mononuclear cell proliferation

determination method

1 reference

21 June 2018

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of transcription, DNA-templated

determination method

negative regulation of T cell activation

determination method

1 reference

21 June 2018

TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of odontogenesis

determination method

1 reference

21 June 2018

Comparative analysis of TGF beta s, BMPs, IGF1, msxs, fibronectin, osteonectin and bone sialoprotein gene expression during normal and in vitro-induced odontoblast differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

lipopolysaccharide-mediated signaling pathway

determination method

positive regulation of protein localization to nucleus

determination method

1 reference

24 April 2018

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

defense response

determination method

1 reference

21 June 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to estradiol

determination method

response to hypoxia

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

hyaluronan catabolic process

determination method

regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

determination method

1 reference

21 June 2018

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to organic cyclic compound

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of protein-containing complex assembly

determination method

protein kinase B signaling

determination method

negative regulation of cell-cell adhesion

determination method

positive regulation of cell migration

determination method

positive regulation of regulatory T cell differentiation

determination method

1 reference

21 June 2018

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cellular response to growth factor stimulus

determination method

1 reference

21 June 2018

Comparative analysis of TGF beta s, BMPs, IGF1, msxs, fibronectin, osteonectin and bone sialoprotein gene expression during normal and in vitro-induced odontoblast differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of pathway-restricted SMAD protein phosphorylation

determination method

4 references

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of regulatory T cell differentiation

determination method

1 reference

21 June 2018

Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

mammary gland branching involved in thelarche

determination method

1 reference

21 June 2018

Mammary gland development in transforming growth factor beta1 null mutant mice: systemic and epithelial effects

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to laminar fluid shear stress

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

myeloid dendritic cell differentiation

determination method

1 reference

21 June 2018

Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

receptor catabolic process

determination method

T-helper 17 cell lineage commitment

determination method

1 reference

21 June 2018

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

positive regulation of histone acetylation

determination method

1 reference

21 June 2018

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of transforming growth factor beta receptor signaling pathway

determination method

positive regulation of phosphatidylinositol 3-kinase activity

determination method

positive regulation of gene expression

determination method

4 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

24 April 2018

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

24 April 2018

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of NAD+ ADP-ribosyltransferase activity

determination method

regulation of cell population proliferation

determination method

1 reference

21 June 2018

The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of skeletal muscle tissue development

determination method

positive regulation of peptidyl-threonine phosphorylation

determination method

positive regulation of isotype switching to IgA isotypes

determination method

positive regulation of cell population proliferation

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of superoxide anion generation

determination method

digestive tract development

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

skeletal muscle tissue development

determination method

1 reference

21 June 2018

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of fibroblast migration

determination method

4 references

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of cell division

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

germ cell migration

determination method

1 reference

21 June 2018

Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of transcription by RNA polymerase II

determination method

6 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of mitotic cell cycle

determination method

positive regulation of SMAD protein signal transduction

determination method

cellular response to insulin-like growth factor stimulus

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

1 reference

21 June 2018

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

embryonic liver development

determination method

1 reference

21 June 2018

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cellular response to ionizing radiation

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

ventricular cardiac muscle tissue morphogenesis

determination method

1 reference

21 June 2018

Maternal rescue of transforming growth factor-beta 1 null mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

heart valve morphogenesis

determination method

1 reference

21 June 2018

Maternal rescue of transforming growth factor-beta 1 null mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

determination method

1 reference

21 June 2018

Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

neural tube development

determination method

1 reference

21 June 2018

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

liver regeneration

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

cellular response to mechanical stimulus

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

heart development

determination method

1 reference

21 June 2018

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of SMAD protein signal transduction

determination method

neural tube closure

determination method

1 reference

21 June 2018

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

determination method

response to immobilization stress

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

BMP signaling pathway

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

membrane protein intracellular domain proteolysis

determination method

positive regulation of transcription, DNA-templated

determination method

4 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

transforming growth factor beta receptor signaling pathway involved in heart development

determination method

1 reference

21 June 2018

Maternal rescue of transforming growth factor-beta 1 null mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

regulation of signaling receptor activity

determination method

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

response to salt

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

osteoclast differentiation

determination method

protein phosphorylation

determination method

4 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of gene expression

determination method

5 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of gene expression

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

negative regulation of biomineral tissue development

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

positive regulation of protein localization to nucleus

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04202&geneProductId=UniProtKB:P04202

determination method

Transforming growth factor-beta, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04202

Transforming growth factor beta, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04202

TGF-beta, propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04202

Identifiers

0 references

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000002678

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000002678

ENSMUSP00000130413

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000130413

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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