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(Q14818020)

English

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.

  • GO:0006977
  • positive regulation of cell cycle arrest by p53-mediated DNA damage response
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