(Q48101938)

8 February 2018

title

The role of Akt-GSK-3beta signaling and synaptic strength in phencyclidine-induced neurodegeneration (English)

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8 February 2018

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Gang Lei

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8 February 2018

Yan Xia

series ordinal

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8 February 2018

Kenneth M Johnson

series ordinal

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8 February 2018

language of work or name

English

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publication date

18 July 2007

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8 February 2018

published in

Neuropsychopharmacology

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8 February 2018

volume

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8 February 2018

issue

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8 February 2018

page(s)

1343-1353

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8 February 2018

Increased phosphorylation of Ser473-Akt, Ser9-GSK-3beta and Ser133-CREB in the rat frontal cortex after MK-801 intraperitoneal injection

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Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia

21 January 2018

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Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain

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Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons

21 January 2018

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

21 January 2018

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The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

21 January 2018

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Neuropharmacology of phencyclidine: basic mechanisms and therapeutic potential

21 January 2018

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The glamour and gloom of glycogen synthase kinase-3

21 January 2018

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Psychotropic drugs affect Ser9-phosphorylated GSK-3 beta protein levels in rodent frontal cortex

21 January 2018

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AKT crystal structure and AKT-specific inhibitors

21 January 2018

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Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

21 January 2018

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Pathophysiologically based treatment interventions in schizophrenia

21 January 2018

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Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

21 January 2018

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Neuronal activity-dependent cell survival mediated by transcription factor MEF2

21 January 2018

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Calcium channel and NMDA receptor activities differentially regulate nuclear C/EBPbeta levels to control neuronal survival

21 January 2018

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PCP: from pharmacology to modelling schizophrenia

21 January 2018

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L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

21 January 2018

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An update on the genetics of schizophrenia

21 January 2018

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Glutamate receptor dysfunction and schizophrenia

21 January 2018

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21 January 2018

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NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death

21 January 2018

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21 January 2018

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Dopamine agonist action of phencyclidine

21 January 2018

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Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

21 January 2018

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Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability

21 January 2018

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Activity-dependent NMDA receptor-mediated activation of protein kinase B/Akt in cortical neuronal cultures

21 January 2018

1 reference

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Diverse psychotomimetics act through a common signaling pathway

21 January 2018

1 reference

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A positive feedback loop between glycogen synthase kinase 3beta and protein phosphatase 1 after stimulation of NR2B NMDA receptors in forebrain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Apoptotic cell death and caspase-3 activation induced by N-methyl-D-aspartate receptor antagonists and their prevention by insulin-like growth factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Ketamine-induced apoptosis in cultured rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Reduction in intracellular calcium levels induces injury in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

The role of NMDA receptor upregulation in phencyclidine-induced cortical apoptosis in organotypic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Differential effects of acute and subchronic administration on phencyclidine-induced neurodegeneration in the perinatal rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

The role of caspase-3 activation in phencyclidine-induced neuronal death in postnatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Functional proteins involved in regulation of intracellular Ca(2+) for drug development: role of calcium/calmodulin-dependent protein kinases in ischemic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Blockade of ionotropic glutamate receptors produces neuronal apoptosis through the Bax-cytochrome C-caspase pathway: the causative role of Ca2+ deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Role of ion flux in the control of c-fos expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Dopamine induces a PI3-kinase-independent activation of Akt in striatal neurons: a new route to cAMP response element-binding protein phosphorylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

N-Methyl-D-aspartate receptor blockade induces neuronal apoptosis in cortical culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Association of AKT1 with schizophrenia confirmed in a Japanese population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Membrane depolarization-mediated survival of sympathetic neurons occurs through both phosphatidylinositol 3-kinase- and CaM kinase II-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Failure to confirm association between AKT1 haplotype and schizophrenia in a Japanese case-control population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Neurobiology of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301511

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1301511

1 reference

8 February 2018

1 reference

8 February 2018