(Q41732724)

8 October 2017

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title

Functions of the BRCA1 and BRCA2 genes (English)

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8 October 2017

Bertwistle D

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8 October 2017

Ashworth A

series ordinal

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8 October 2017

publication date

1 February 1998

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Current Opinion in Genetics & Development

8 October 2017

published in

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8 October 2017

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8 October 2017

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8 October 2017

page(s)

14-20

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Inherited breast and ovarian cancer.

8 October 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Hereditary predisposition to breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Recent advances in understanding of genetic susceptibility to breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Breast cancer genes--what are the real risks?

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Does this have a familiar RING?

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 protein products ... Functional motifs...

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Identification of the breast cancer susceptibility gene BRCA2

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Internal repeats in the BRCA2 protein sequence

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

The BRC repeats are conserved in mammalian BRCA2 proteins

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 expression is not directly responsive to estrogen

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Aberrant subcellular localization of BRCA1 in breast cancer

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Location of BRCA1 in human breast and ovarian cancer cells

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Response: Location of BRCA1 in Human Breast and Ovarian Cancer Cells

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 is secreted and exhibits properties of a granin

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 protein products: Antibody specificity…

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 is localized in cytoplasmic tube-like invaginations in the nucleus

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Tumor suppressor gene mutations in mice

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

A human BRCA1 gene knockout

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Transcriptional activation by BRCA1

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Transcriptional activation functions in BRCA2

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

BRCA1 is a component of the RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

DNA repair: RAD alert

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Cancer-susceptibility genes. Gatekeepers and caretakers

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

p53 mutations in BRCA1-associated familial breast cancer

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Abnormal centrosome amplification in the absence of p53.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

A polymorphic stop codon in BRCA2

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980056-7

7 January 2021

10.1016/S0959-437X(98)80056-7

Identifiers

DOI

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8 October 2017

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