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Mitochondrial dysfunction contributes to oncogene-induced senescence.
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Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
title
Mitochondrial dysfunction contributes to oncogene-induced senescence
(English)
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stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
author
Xavier Deschênes-Simard
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4
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Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Gerardo Ferbeyre
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5
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Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
author name string
Olga Moiseeva
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1
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Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Véronique Bourdeau
series ordinal
2
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PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Antoine Roux
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
language of work or name
English
0 references
publication date
15 June 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
published in
Molecular and Cellular Biology
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stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
volume
29
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stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
issue
16
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
page(s)
4495-4507
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Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
cites work
Tumor suppressors and cell metabolism: a recipe for cancer growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Oxygen free radicals in cell senescence: are they signal transducers?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Mitochondria: more than just a powerhouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Mitochondria: dynamic organelles in disease, aging, and development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Glycolytic enzymes can modulate cellular life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Intrinsic tumour suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
A DNA damage checkpoint response in telomere-initiated senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
p53 has a direct apoptogenic role at the mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Superoxide activates mitochondrial uncoupling proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
The biochemistry of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
PML is induced by oncogenic ras and promotes premature senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
A model for p53-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Oxidative DNA damage and senescence of human diploid fibroblast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Cellular targets for transformation by the adenovirus E1A proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
22 September 2017
Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
25 September 2017
The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
17 June 2018
Differential regulation of antioxidant enzymes in response to oxidants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
17 June 2018
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
20 August 2018
Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
20 August 2018
Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
20 August 2018
Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
20 August 2018
Transformation of normal human cells in the absence of telomerase activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737
retrieved
20 August 2018
Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19528227
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The tumor-suppressive functions of the human INK4A locus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19528227
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19528227
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19528227
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A high glycolytic flux supports the proliferative potential of murine embryonic stem cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19528227
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.01868-08
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PMC publication ID
2725737
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PubMed publication ID
19528227
1 reference
stated in
Europe PubMed Central
PMC publication ID
2725737
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
ResearchGate publication ID
26293750
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