(Q34611868)

3 August 2017

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title

Getting under the skin of epidermal morphogenesis (English)

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3 August 2017

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Elaine Fuchs

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3 August 2017

Srikala Raghavan

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3 August 2017

language of work or name

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1 March 2002

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3 August 2017

published in

Nature Reviews Genetics

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

199-209

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Location of stem cells of human hair follicles by clonal analysis

3 August 2017

cites work

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Out of Eden: stem cells and their niches

31 March 2020

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Morphogenesis and renewal of hair follicles from adult multipotent stem cells

31 March 2020

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Involvement of follicular stem cells in forming not only the follicle but also the epidermis

31 March 2020

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Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

31 March 2020

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Stem cell patterning and fate in human epidermis

31 March 2020

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Three clonal types of keratinocyte with different capacities for multiplication

31 March 2020

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Epidermal stem cells: markers, patterning and the control of stem cell fate

31 March 2020

1 reference

Enrichment for murine keratinocyte stem cells based on cell surface phenotype

31 March 2020

1 reference

p63 identifies keratinocyte stem cells

31 March 2020

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p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

31 March 2020

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p63 is a p53 homologue required for limb and epidermal morphogenesis

31 March 2020

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Deregulated expression of c-Myc depletes epidermal stem cells

31 March 2020

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c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

31 March 2020

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Contrasting localization of c-Myc with other Myc superfamily transcription factors in the human hair follicle and during the hair growth cycle

31 March 2020

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WNT signaling in the control of hair growth and structure.

31 March 2020

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Sonic hedgehog signaling is essential for hair development

31 March 2020

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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

31 March 2020

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Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

31 March 2020

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beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

31 March 2020

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Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

31 March 2020

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Notch signalling and the control of cell fate choices in vertebrates.

31 March 2020

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Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

31 March 2020

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Notch signaling: cell fate control and signal integration in development

31 March 2020

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The Notch signalling pathway in hair growth

31 March 2020

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Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.

31 March 2020

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The p53 family member genes are involved in the Notch signal pathway

31 March 2020

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Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

31 March 2020

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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis

31 March 2020

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Presenilin 1 independently regulates beta-catenin stability and transcriptional activity

31 March 2020

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Presenilin 1 regulates beta-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion

31 March 2020

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Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

31 March 2020

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The notch intracellular domain can function as a coactivator for LEF-1

31 March 2020

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At the roots of a never-ending cycle.

31 March 2020

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Neural patterning in the vertebrate embryo

31 March 2020

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The status of Wnt signalling regulates neural and epidermal fates in the chick embryo

31 March 2020

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Keratin 10 gene expression during differentiation of mouse epidermis requires transcription factors C/EBP and AP-2

31 March 2020

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Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia

31 March 2020

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Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation

31 March 2020

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Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes

31 March 2020

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Klf4 is a transcription factor required for establishing the barrier function of the skin

31 March 2020

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

31 March 2020

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

31 March 2020

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Limb and skin abnormalities in mice lacking IKKalpha

31 March 2020

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IKKalpha controls formation of the epidermis independently of NF-kappaB.

31 March 2020

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Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

31 March 2020

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NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

31 March 2020

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Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

31 March 2020

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Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

31 March 2020

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Regulation of terminal differentiation of cultured human keratinocytes by vitamin A.

31 March 2020

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Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization

31 March 2020

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Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse

31 March 2020

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Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

31 March 2020

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Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

31 March 2020

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Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene

31 March 2020

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Regulation of a human epidermal keratin gene: sequences and nuclear factors involved in keratinocyte-specific transcription

31 March 2020

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Transcription factor AP2 and its role in epidermal-specific gene expression

31 March 2020

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The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression

31 March 2020

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The transglutaminase 1 enzyme is variably acylated by myristate and palmitate during differentiation in epidermal keratinocytes

31 March 2020

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Identification of a functional determinant of differentiation-dependent expression in the involucrin gene

31 March 2020

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Regulation of gene expression in developing epidermal epithelia

31 March 2020

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Defining the regulatory factors required for epidermal gene expression

31 March 2020

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Identification and dissection of an enhancer controlling epithelial gene expression in skin

31 March 2020

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Epidermal signal transduction and transcription factor activation in activated keratinocytes.

31 March 2020

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Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway

31 March 2020

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AP-1 in mouse development and tumorigenesis

31 March 2020

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c-Jun is essential for normal mouse development and hepatogenesis

31 March 2020

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Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

31 March 2020

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Functions of c-Jun in liver and heart development

31 March 2020

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JunB can substitute for Jun in mouse development and cell proliferation

31 March 2020

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Are desmosomes more than tethers for intermediate filaments?

31 March 2020

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Directed actin polymerization is the driving force for epithelial cell-cell adhesion

31 March 2020

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Desmosomal adhesion regulates epithelial morphogenesis and cell positioning

31 March 2020

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

31 March 2020

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APC mutations occur early during colorectal tumorigenesis

31 March 2020

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A common human skin tumour is caused by activating mutations in beta-catenin

31 March 2020

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Expression of E-cadherin in skin carcinomas

31 March 2020

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Cytomechanics of cadherin-mediated cell-cell adhesion

31 March 2020

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The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn

31 March 2020

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Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

31 March 2020

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Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome

31 March 2020

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Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma

31 March 2020

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α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

31 March 2020

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Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes

31 March 2020

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Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination

31 March 2020

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Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival

31 March 2020

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Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.

31 March 2020

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Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice

31 March 2020

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Structure and function of hemidesmosomes: more than simple adhesion complexes

31 March 2020

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Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosa

31 March 2020

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Keratinocyte growth factor is required for hair development but not for wound healing

31 March 2020

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Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

31 March 2020

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c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

31 March 2020

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Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice

31 March 2020

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The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF

31 March 2020

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Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

31 March 2020

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The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase

31 March 2020

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Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

31 March 2020

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Strain-dependent epithelial defects in mice lacking the EGF receptor

31 March 2020

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Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

31 March 2020

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Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

31 March 2020

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Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression

31 March 2020

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

31 March 2020

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Interleukin 20: discovery, receptor identification, and role in epidermal function

31 March 2020

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Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

31 March 2020

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Actin dynamics and cell-cell adhesion in epithelia

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG758

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Dimensions Publication ID

3 August 2017

1051188168

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