SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this stu... more SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre‐operative SARS‐CoV‐2 infection were compared with those without previous SARS‐CoV‐2 infection. The primary outcome measure was 30‐day postoperative mortality. Logistic regression models were used to calculate adjusted 30‐day mortality rates stratified by time from diagnosis of SARS‐CoV‐2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre‐operative SARS‐CoV‐2 diagnosis. Adjusted 30‐day mortality in patients without SARS‐CoV‐2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre‐operative SARS‐CoV‐2 diagnosis, mortality was increased in patients having surgery wi...
SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critica... more SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri‐operative or prior SARS‐CoV‐2 were at further increased risk of venous thromboembolism. We conducted a planned sub‐study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS‐CoV‐2 diagnosis was defined as peri‐operative (7 days before to 30 days after surgery); recent (1–6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre‐operative anti‐coagulation for baseline comorbidities was no...
INTRODUCTION: Improving health services worldwide has led to a gradually aging population. Sarcop... more INTRODUCTION: Improving health services worldwide has led to a gradually aging population. Sarcopenia has been identified as an important contributor to health costs in elderly women in developed countries. The lifestyle and access to medical services is vastly different in the developing countries like India. The present research was conducted to study the status of sarcopenia among perimenopausal and postmenopausal women of India. METHODS: Institutional review board approval for the study was obtained from institutional ethical committee. Women aged 40 years or more, having no complaints, and coming to hospital as companions were enrolled after taking consent. A detailed history was taken and activity levels were classified according to the ICATUS 2016 (International Classification for Time-Use Statistics). Muscle strength was evaluated by handgrip strength, gait speed, and appendicular skeletal mass measurement. Serum estradiol, vitamin D3, fasting plasma glucose, and fasting ins...
International journal of reproduction, contraception, obstetrics and gynecology, 2018
Intrauterine Insemination (IUI) along with controlled ovarian stimulation has been a widely used ... more Intrauterine Insemination (IUI) along with controlled ovarian stimulation has been a widely used method in management of women with infertility. IUI remains a relatively inexpensive, less invasive and easy to perform procedure, which if timed well can give favorable results. It is used in male factor infertility, minimal to mild endometriosis, PCOS, cervical factor or unexplained infertility. IUI has various determinants of success. Of these, sperm morphology, method of sperm preparation, cause of infertility, ovulation induction regime used, agent for ovulation trigger, etc. are important. Along with these, time interval between ovulation induction and IUI and time interval between sperm preparation and IUI are of definite clinical relevance.
Introduction: Thyroid dysfunction is reported in 8.25% of pregnant women in Indian subcontinent. ... more Introduction: Thyroid dysfunction is reported in 8.25% of pregnant women in Indian subcontinent. About two thirds of these women have subclinical hypothyroidism and the rest have overt hypothyroidism. Aim: To study the prevalence and impact of Thyroid Peroxidase (TPO) antibodies on obstetric and perinatal outcome in a tertiary health centre. Materials and Methods: This was a prospective cohort study conducted in antenatal clinic of Department of Obstetrics and Gynaecology in collaboration with Department of Biochemistry at King George Medical University, Lucknow, India. Total 230 antenatal women upto 20 weeks of gestational age were recruited, venous blood sample was assessed for serum TSH and TPO Ab and women were classified as subclinical or overt hypothyroid. Subsequently, serum TSH was repeated at interval of 4-6 weeks after initiation of treatment. All the enrolled women were followed for obstetric and perinatal outcome. Results: The prevalence of TPO Ab in pregnant women was 4...
SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this stu... more SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre‐operative SARS‐CoV‐2 infection were compared with those without previous SARS‐CoV‐2 infection. The primary outcome measure was 30‐day postoperative mortality. Logistic regression models were used to calculate adjusted 30‐day mortality rates stratified by time from diagnosis of SARS‐CoV‐2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre‐operative SARS‐CoV‐2 diagnosis. Adjusted 30‐day mortality in patients without SARS‐CoV‐2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre‐operative SARS‐CoV‐2 diagnosis, mortality was increased in patients having surgery wi...
SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critica... more SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri‐operative or prior SARS‐CoV‐2 were at further increased risk of venous thromboembolism. We conducted a planned sub‐study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS‐CoV‐2 diagnosis was defined as peri‐operative (7 days before to 30 days after surgery); recent (1–6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre‐operative anti‐coagulation for baseline comorbidities was no...
INTRODUCTION: Improving health services worldwide has led to a gradually aging population. Sarcop... more INTRODUCTION: Improving health services worldwide has led to a gradually aging population. Sarcopenia has been identified as an important contributor to health costs in elderly women in developed countries. The lifestyle and access to medical services is vastly different in the developing countries like India. The present research was conducted to study the status of sarcopenia among perimenopausal and postmenopausal women of India. METHODS: Institutional review board approval for the study was obtained from institutional ethical committee. Women aged 40 years or more, having no complaints, and coming to hospital as companions were enrolled after taking consent. A detailed history was taken and activity levels were classified according to the ICATUS 2016 (International Classification for Time-Use Statistics). Muscle strength was evaluated by handgrip strength, gait speed, and appendicular skeletal mass measurement. Serum estradiol, vitamin D3, fasting plasma glucose, and fasting ins...
International journal of reproduction, contraception, obstetrics and gynecology, 2018
Intrauterine Insemination (IUI) along with controlled ovarian stimulation has been a widely used ... more Intrauterine Insemination (IUI) along with controlled ovarian stimulation has been a widely used method in management of women with infertility. IUI remains a relatively inexpensive, less invasive and easy to perform procedure, which if timed well can give favorable results. It is used in male factor infertility, minimal to mild endometriosis, PCOS, cervical factor or unexplained infertility. IUI has various determinants of success. Of these, sperm morphology, method of sperm preparation, cause of infertility, ovulation induction regime used, agent for ovulation trigger, etc. are important. Along with these, time interval between ovulation induction and IUI and time interval between sperm preparation and IUI are of definite clinical relevance.
Introduction: Thyroid dysfunction is reported in 8.25% of pregnant women in Indian subcontinent. ... more Introduction: Thyroid dysfunction is reported in 8.25% of pregnant women in Indian subcontinent. About two thirds of these women have subclinical hypothyroidism and the rest have overt hypothyroidism. Aim: To study the prevalence and impact of Thyroid Peroxidase (TPO) antibodies on obstetric and perinatal outcome in a tertiary health centre. Materials and Methods: This was a prospective cohort study conducted in antenatal clinic of Department of Obstetrics and Gynaecology in collaboration with Department of Biochemistry at King George Medical University, Lucknow, India. Total 230 antenatal women upto 20 weeks of gestational age were recruited, venous blood sample was assessed for serum TSH and TPO Ab and women were classified as subclinical or overt hypothyroid. Subsequently, serum TSH was repeated at interval of 4-6 weeks after initiation of treatment. All the enrolled women were followed for obstetric and perinatal outcome. Results: The prevalence of TPO Ab in pregnant women was 4...
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