Papers by Ghadeer Al-shaikh
Obstetrics & Gynecology, May 1, 2014
The objective of this study was to review outcome of vaginal hysterectomy with uterosacral suspen... more The objective of this study was to review outcome of vaginal hysterectomy with uterosacral suspension compared with sacrospinous hysteropexy for uterine prolapse. A retrospective chart review of the cases at a tertiary referral hospital in Riyadh, Saudi Arabia, from January 2006 to December 2012. Sacrospinous hysteropexy was done unilaterally on the right sacrospinous ligament. Concomitant surgery (anterior, posterior colporrhaphy, and incontinent surgeries) were performed when necessary. Fifty cases were identified, 26 cases of vaginal hysterectomy with uterosacral suspension and 24 cases of sacrospinous hysteropexy. Mean age was 55.7 years and 52.1 years, respectively. Mean follow-up was 22 months in the vaginal hysterectomy with uterosacral suspension group and 11 months in the sacrospinous hysteropexy group. No serious intraoperative complications were observed. Resolution of bulge symptom was observed in 2 of 26 (7.6%) of the vaginal hysterectomy with uterosacral suspension group and 22 of 24 (91.6%) of the sacrospinous hysteropexy group (P>.05). Objective anatomical success was seen in 26 of 26 (100%) of the vaginal hysterectomy with uterosacral suspension group and 21 of 24 (87%) of the sacrospinous hysteropexy group (P>.05). Recurrence of anterior prolapse was seen in two cases of vaginal hysterectomy with uterosacral suspension (7.6%) and eight cases of sacrospinous hysteropexy (33.3%) (P<.05). One case of pulmonary embolism (3.8%) and one (3.8%) case of ureter kinking that required only stent placement was observed in the vaginal hysterectomy with uterosacral suspension series. A sacrospinous hysteropexy stitch was removed in two patients (8.3%), one for persistent buttock pain and right side labial perineal numbness and other one for vaginal pain. Our study suggests that although both procedures have similar subjective results, there is a trend toward more objective recurrences in the sacrospinous hysteropexy group.
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Anaesthesia, 2021
SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this stu... more SummaryPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre‐operative SARS‐CoV‐2 infection were compared with those without previous SARS‐CoV‐2 infection. The primary outcome measure was 30‐day postoperative mortality. Logistic regression models were used to calculate adjusted 30‐day mortality rates stratified by time from diagnosis of SARS‐CoV‐2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre‐operative SARS‐CoV‐2 diagnosis. Adjusted 30‐day mortality in patients without SARS‐CoV‐2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre‐operative SARS‐CoV‐2 diagnosis, mortality was increased in patients having surgery wi...
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Annals of Surgical Oncology, 2006
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Anaesthesia, 2021
SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critica... more SummarySARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri‐operative or prior SARS‐CoV‐2 were at further increased risk of venous thromboembolism. We conducted a planned sub‐study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS‐CoV‐2 diagnosis was defined as peri‐operative (7 days before to 30 days after surgery); recent (1–6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre‐operative anti‐coagulation for baseline comorbidities was no...
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La Prensa Medica, 2016
Association of Socio Economic Status with Gestational Diabetes Mellitus among Saudi Women Women w... more Association of Socio Economic Status with Gestational Diabetes Mellitus among Saudi Women Women with Gestational Diabetes Mellitus (GDM) are at risk of adverse obstetric and perinatal outcome. The association between GDM and socioeconomic status is not well established. The purpose of this study is to find the association between socioeconomic factors and GDM.
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Saudi Medical Journal, May 1, 2012
To explore the experience of interns in sensitive area examination during their undergraduate med... more To explore the experience of interns in sensitive area examination during their undergraduate medical course and identify factors interfering with such examinations. A cross sectional study was carried out from May to June 2010. Interns (n=315) at King Saud University College of Medicine were invited via email to complete a web-based questionnaire developed using surveymonkey.com. Out of 315 interns, 211 completed the questionnaire; 60% males and 40% females. The mean percentage of interns who never performed any of these examinations was 28.9% for digital rectal examination, 17.5% for breast, 43.1% for female pelvic examination, 13.3% for inguinal (hernia), and 34.6% for male external genitalia. Compared to females, male students conducted more rectal examinations (87 versus 63, p<0.005), and male external genitalia examinations (112 versus 26, p<0.001). On the other hand, compared to male students, females conducted more pelvic examination (68 versus 52, p=0.03) and breast examinations (92 versus 82, p=0.27). The most common reasons for not performing sensitive area examinations included patient's refusal (33.1%), and examining patients of opposite gender (27.6%). Confidence in performance of these examinations was correlated to increased frequency of the examination. This study highlights that most common factors interfering with the students' conducting sensitive area examinations are patient's refusal and examining patients of the opposite sex. There is a strong correlation between increased frequency of conducting an examination and student's confidence in performance.
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Pakistan Journal of Medical Sciences, 1969
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Saudi Medical Journal, 2014
To assess the level of knowledge regarding cervical cancer and the acceptance of the human papill... more To assess the level of knowledge regarding cervical cancer and the acceptance of the human papilloma virus (HPV) vaccine among Saudi female students in health colleges. This cross-sectional study of a convenient sample encompassed 1400 students in Health Colleges at Princess Nora Bint Abdul Rahman University, Riyadh, Saudi Arabia was conducted between December 2013 and February 2014. A self-administrated questionnaire was distributed to all participants. Data collected included socio-demographic data, knowledge of cervical cancer risk factors and clinical presentation, Pap smear, and HPV vaccine acceptance. The questionnaire reliability as tested by Cronbach's alpha was 0.82. The response rate was 89.9%, and data analysis revealed that 95.7% of students had poor knowledge level. The Pap smear was poorly recognized as a screening tool, with 46.7% of students having heard of the test. Senior and medical students had a significantly higher knowledge score. Father's health profe...
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STROBE Statement. (DOC 92.5Â kb)
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Purpose: and interobserver reproducibility of this method. Materials and Methods: from hospital s... more Purpose: and interobserver reproducibility of this method. Materials and Methods: from hospital staff and patients attending the gynecological clinic over a period of six months. All €€€€€€€€€€€€€€€€€€€€€€€€€€€€€€€€ Results: @@@@@@@@@@@@@@@@@@@@@ @@@@@@@@@@@@@@@@ @@@@@@@@@@@@@@@@-der volume. Conclusion: females yields reproducible measurements and can be used as a reference for future understand-disorders.
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Sultan Qaboos University Medical Journal, 2013
Urinary tract infections (UTIs) are one of the most frequent clinical bacterial infections in wom... more Urinary tract infections (UTIs) are one of the most frequent clinical bacterial infections in women, accounting for nearly 25% of all infections. Around 50–60% of women will develop UTIs in their lifetimes. Escherichia coli is the organism that causes UTIs in most patients. Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis. Although the initial treatment is antimicrobial therapy, use of different prophylactic regimens and alternative strategies are available to reduce exposure to antibiotics.
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Saudi Medical Journal, 2012
To evaluate the prevalence, indications, and factors associated with successful induction of labo... more To evaluate the prevalence, indications, and factors associated with successful induction of labor (IOL), and maternal and neonatal outcomes. All women booked for IOL at King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia from April 2010 to March 2011 were included. The characteristics of women who had successful IOL were compared to those who delivered by cesarean section (CS). A multivariable logistic regression analysis was performed to evaluate the factors associated with successful IOL. During the study period, 564 women had IOL. The prevalence rate of IOL was 16%. Vaginal delivery was achieved in 472 (84%) women. The most common indications for IOL were post-term pregnancy in 174 (31%), and diabetes mellitus in 131 (23.2%) of the participants. Maternal characteristics associated with risk of CS were nulliparity (odds ratio: 1.58; 95% confidence interval: 1.09-2.320; p=0.01), and high maternal body mass index (p=0.01). Neonates of women with s...
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Sultan Qaboos University Medical Journal, Jun 25, 2013
Urinary tract infections (UTIs) are one of the most frequent clinical bacterial infections in wom... more Urinary tract infections (UTIs) are one of the most frequent clinical bacterial infections in women, accounting for nearly 25% of all infections. Around 50-60% of women will develop UTIs in their lifetimes. Escherichia coli is the organism that causes UTIs in most patients. Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis. Although the initial treatment is antimicrobial therapy, use of different prophylactic regimens and alternative strategies are available to reduce exposure to antibiotics.
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Abstract: Background: Societal perception of smokers, and reasons behind them smoking both reflec... more Abstract: Background: Societal perception of smokers, and reasons behind them smoking both reflect acceptance or rejection of smoking behaviour and can reframe tobacco prevention and/or cessation programs to be more effective in tobacco control. This study aimed at targeting the social unacceptability of smoking amongst Saudi females and considering their opinions of the reasons behind smoking amongst both genders. Methodology: We followed a cross-sectional approach towards data collection from a sample of pregnant women seen at the antenatal clinic at King Khalid University hospital, irrespective of their gestational age. The data was collected using a pretested, anonymous, self administered questionnaire. Results: 1208 pregnant women were included in our study. Their mean age was 29 + 6 years, and their mean gestational age was 29.6 + 7 weeks. Most women (88%) either agreed or strongly agreed that exposure to smoking may harm the foetus, and only 3.5 % of them would accept to smok...
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British Journal of Surgery
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numb... more Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst ...
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International Journal of Gynecological and Obstetrical Research, 2013
Background : Societal perception of smokers, and reasons behind them smoking both reflect accepta... more Background : Societal perception of smokers, and reasons behind them smoking both reflect acceptance or rejection of smoking behaviour and can reframe tobacco prevention and/or cessation programs to be more effective in tobacco control. This study aimed at targeting the social unacceptability of smoking amongst Saudi females and considering their opinions of the reasons behind smoking amongst both genders. Methodology : We followed a cross-sectional approach towards data collection from a sample of pregnant women seen at the antenatal clinic at King Khalid University hospital, irrespective of their gestational age. The data was collected using a pretested, anonymous, self administered questionnaire. Results : 1208 pregnant women were included in our study. Their mean age was 29 + 6 years, and their mean gestational age was 29.6 + 7 weeks. Most women (88%) either agreed or strongly agreed that exposure to smoking may harm the foetus, and only 3.5% of them would accept to smoke if they were offered a cigarette by their husbands. The top reported reasons for smoking amongst males and females were: association with tobacco using friend, reduction of stress, and manifestation of masculinity or gender equality. Pregnant women were not impressed by smokers, and as less than 1% of them considered them attractive and about 25% of them believed male and female smokers feel insecure. Conclusion : The social disapproval of smoking behaviour in this study was prominent especially towards female smokers. Reasons behind smoking are still blamed on friends, family members and peer pressure. Such results are important in shaping tobacco prevention and control programs
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Factor XII, (Hageman factor) is a serine protease zymogen that, when activated, initiates the int... more Factor XII, (Hageman factor) is a serine protease zymogen that, when activated, initiates the intrinsic pathway of blood coagulation. Patients with Factor XII deficiency do not have excessive bleeding tendency despite prolongation of the activated partial thromboplastin time (APTT) in their serum. Postpartum Hemorrhage (PPH) is a potentially fatal obstetric complication, and its presence in the setting of a prolonged APTT can be worrisome to the treating obstetrician. Here, we report a case of PPH with prolonged APTT due to underlying factor XII deficiency who was successfully managed conservatively. The findings of this case report show that FXII deficient patients presenting with PPH can effectively be managed conservatively in the same way as other individuals with normal FXII levels.
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Medical Teacher
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International journal of women's health, 2018
Stress urinary incontinnce (SUI) is a common condition among women. The usual approach to treatme... more Stress urinary incontinnce (SUI) is a common condition among women. The usual approach to treatment of SUI is a stepwise plan from conservative to surgical procedures. A vaginal pessary is one of the commonly used conservative treatments that offer symptomatic improvement for women with incontinence. This review provides a critical analysis of the benefits and shortcomings offered by vaginal pessaries to patients affected by SUI, with a particular focus on indications, advantages, quality of life, patient satisfaction, and potential complications. To obtain the required information, an extensive search of PubMed and Cochrane databases was performed, covering the time frame from January 2000 to December 2016. We also surveyed the published guidelines of American Urological Association, Canadian Urological Association, American Urogynecological Society, National Institutes of Health (USA), and National Institute for Health and Care Excellence (UK). A total of 192 original research pap...
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Papers by Ghadeer Al-shaikh